주제분류
자료유형
등재정보
발행기관
전체 선택해제
총 5건 검색
본문검색 결과만 보기
-
Resveratrol Inhibits Nicotinic Stimulation-Evoked Catecholamine Release from the Adrenal Medulla
Seong-ChangWoo, Gwang-MoonNa, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.4 5 155-164 (10 pages)
a time- and dose- dependent fashion. Also, in the presence of resveratrol (30ՌM), the secretory responses of CA evoked by veratridine 8644 (an activator of voltage-dependent Na＋ channels, 100ՌM), Bay-K-8644 (a L-type dihydropyridine Ca2＋ channel activator, 10ՌM), and cyclopiazonic acid (a cytoplasmic Ca2＋-ATPase inhibitor, 10ՌM) were significantly reduced. In the simultaneous presence of resveratrol (30ՌM) and L-NAME (an inhibitor of NO synthase, 30ՌM), the... -
The Inhibition of TREK2 Channel by an Oxidizing Agent, 5,5'-dithio- bis (2-nitrobenzoic acid), via Interaction with the C-terminus Distal to the 353rd Amino Acid
KyoungSunPark, HyoweonBang, Eun-YoungShin, ChanHyungKim, YangmiKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.4 13 211-215 (5 pages)
TRAAK (TWIK-Related Arachidonic acid Activated K＋ channels) were expressed in COS-7 cells, and the channel activities were recorded from inside-out membrane patches using holding potential of −40 mV in symmetrical 150 mM K＋ solution. Intra</SUP>cellular application of an oxidizing agent, 5,5'-dithio-bis (2-nitrobenzoic acid) (DTNB), markedly decreased the activity of the TREK2, and the activity was partially reversed by the reducing agent, dithiothreitol (DTT). In order to examine... -
The Inhibitory Effects of Hydrogen Sulfide on Pacemaker Activity of Interstitial Cells of Cajal from Mouse Small Intestine
ShankarPrasadParajuli, SeokChoi, JunLee, YoungDaeKim, ChanGukPark, ManYooKim, HyunIlKim, CheolHoYeum, JaeYeoulJun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.2 4 83-89 (7 pages)
of H2S on pacemaker activity were investigated using whole-cell patch-clamp technique, intracellular Ca2＋ analysis at 30oC and RT-PCR in cultured mouse intestinal ICC. Exogenously applied sodium hydrogen sulfide (NaHS), a donor of hydrogen sulfide, caused a slight tonic inward current on pacemaker activity in ICC at low concentrations (50 and 100</SUP>ՌM), but at high concentration (500ՌM and 1 mM) it seemed to cause light tonic inward currents and then inhibited pacemaker... -
Mechanisms of Selective Antimicrobial Activity of Gaegurin 4
HeejeongKim, ByeongJaeLee, MunHanLee, SeongGeunHong, PanDongRyu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.1 7 39-48 (10 pages)
M. luteus (2.5</SUP>Ռg/ml) was faster and larger than that from Gram-negative E. coli (75Ռg/ml), while that from RBC was negligible even at higher concentration (100Ռg/ml). GGN4 induced larger conductances in the planar bilayers which were formed with lipids extracted from Gram-positive B. subtilis than in those from E. coli (p＜0.01), however, the effects of GGN4 were not selective in the bilayers formed with lipids from E. coli and red blood cells. Addition of an acidic... -
Response of IKr and hERG Currents to the Antipsychotics Tiapride and Sulpiride
Su-HyunJo, So-YoungLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 9 305-310 (6 pages)
delayed rectifier K＋ currents in guinea pig cardiomyocytes. Neither the amplitude of the hERG outward currents measured at the end of the voltage pulse, nor the amplitude of hERG tail currents, showed any concentration-dependent changes with either tiapride or sulpiride (3∼300</SUP>ՌM). However, our findings did show that tiapride increased the potential for half-maximal activation (V1/2) of HERG at 10∼300ՌM, whereas sulpiride increased the maximum conductance (Gmax) at 3,...
