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Caffeic acid phenethyl ester protects against photothrombotic cortical ischemic injury in mice
SunAeHwang, ChiDaeKim, WonSukLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 11 101-110 (10 pages)
we aimed to investigate the neuroprotective effects of caffeic acid phenethyl ester (CAPE), an active component of propolis purified from honeybee hives, on photothrombotic cortical ischemic injury in mice. Permanent focal ischemia was achieved in the medial frontal and somatosensory cortices of anesthetized male C57BL/6 mice by irradiation of the skull with cold light laser in combination with systemic administration of rose bengal. The animals were treated with CAPE (0.5-5 mg/kg, i.p.) twice 1... -
Neuroprotective effect of caffeic acid phenethyl ester in 3-nitropropionic acid-induced striatal neurotoxicity
JiaBak, HeeJungKim, SeongYunKim, Yun-SikChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.3 7 279-286 (8 pages)
Caffeic acid phenethyl ester (CAPE), derived from honeybee hives, is a bioactive compound with strong antioxidant activity. This study was designed to test the neuroprotective effect of CAPE in 3-nitropropionic acid (3NP)-induced striatal neurotoxicity, a chemical model of Huntington’s disease (HD). Initially, to test CAPE’s antioxidant activity, a 2,2’-azino-bis-3-ethylbenzthiazoline-6-sulfonic acid (ABTS) antioxidant assay was employed, and CAPE showed a strong direct radicalscavenging eff... -
The Effect of Caffeic Acid on Wound Healing in Skin-incised Mice
HoSunSong, TaeWookPark, UyDongSohn, YongKyooShin, ByungChulChoi, ChangJongKim, SangSooSim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.6 9 343-348 (6 pages)
caffeic acid in skin-incised mice. Caffeic acid showed significant effects on anti-inflammatory activity and wound healing, such as myeloperoxidase activity, lipid peroxidation, phospholipase A2 activity and collagen-like polymer synthesis, in incised-wound tissue. On the other hand, it significantly stimulated collagen-like polymer synthesis in NIH 3T3 fibroblast cells, while inhibited both silica-induced reactive oxygen species generation and melittin-induced arachidonic acid release and PGE2... -
Caffeic Acid Phenethyl Ester Inhibits the PKC-Induced IL-6 Gene Expression in the Synoviocytes of Rheumatoid Arthritis Patients
Gang-MinHur, Yin-BangHwang, Jae-HeunLee, So-HyunBae, Ji-SunPark, Choong-JaeLee, Jeong-HoSeok 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 11 363-368 (6 pages)
To gain insight on the role of pro-inflammatory cytokines in the pathogenesis and treatment of rheumatoid arthritis (RA), the phorbol 12-myristate 13-acetate (PMA)-induced IL-6 gene expression and the effect of caffeic acid phenethyl ester (CAPE) on the PMA-induced IL-6 gene expression were investigated in human fibroblast-like synoviocytes (FLSs). Synovial tissue samples were obtained from rheumatoid arthritis patients, and FLSs were isolated. The cells were stimulated with PMA (100 nM) for 6... -
Potential in vitro Protective Effect of Quercetin, Catechin, Caffeic Acid and Phytic Acid against Ethanol-Induced Oxidative Stress in SK-Hep-1 Cells
Lee. Ki-Mo, Kang. Hyung-Sik, Yun. Chul-Ho, Kwak. Hahn-Shik 한국응용약물학회 Biomolecules & therapeutics 7 Pages
한국응용약물학회 Biomolecules & therapeutics 2012, Vol.20 No.5 492-498 (7 pages)
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The Effect of Caffeic Acid on the Antinociception and Mechanisms in Mouse
Park. Soo-Hyun, Sim. Yun-Beom, Kim. Seon-Mi, Lee. Jin-Koo, Jung. Jun-Sub, Suh. Hong-Won 한국응용생명화학회 Journal of the Korean Society for Applied Biological Chemistry 6 Pages
한국응용생명화학회 Journal of the Korean Society for Applied Biological Chemistry 2011, Vol.54 No.2 177-182 (6 pages)
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Simultaneous Determination of Benzoic Acid, Caffeic Acid and Chlorogenic Acid in Seeds of Eriobotrya japonica and their Antibacterial Effect
Jeong. Jun-Mo, Lee. Kyoung-In, Kim. Sun-Min 한국응용생명화학회 Journal of applied biological chemistry 5 Pages
한국응용생명화학회 Journal of applied biological chemistry 2014, Vol.57 No.1 89-93 (5 pages)
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Antineurodegenerative Effect of Phenolic Extracts and Caffeic Acid Derivatives in Romaine Lettuce on Neuron-Like PC-12 Cells
Im. Sung-Eun, Yoon. Hyung-Eun, Nam. Tae-Gyu, Heo. Ho-Jin, Lee. Chang-Yong, Kim. Dae-Ok 한국식품영양과학회 Journal of medicinal food 6 Pages
한국식품영양과학회 Journal of medicinal food 2010, Vol.13 No.4 779-784 (6 pages)
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품종별 들깻잎 열수추출물의 caffeic acid와 rosmarinic acid의 함량 및 항산화력 비교
이현순, 이현아, 홍충의, 양성용, 홍성유, 박상률, 이호정, 이광원, Lee. Hyun-Sun, Lee. Hyun-Ah, Hong. Chung-Oui, Yang. Sung-Yong, Hong. Sung-Yu, Park. Sang-Yul, Lee. Ho- 한국식품과학회 한국식품과학회지 5 Pages
한국식품과학회 한국식품과학회지 2009, Vol.41 No.3 302-306 (5 pages)
mM $FeSO_4$ $7H_2O/g$ DM으로 높았고, DPPH 결과에서는 $SC_50$값이 동글2호가 241 ${mu}g$ DM/mL로 가장 항산화력이 높았고, 그 다음으로 261 ${mu}g$ DM/mL로 보라들깨였다. 플라보노이드 함유량 측정에서는 늘보라들깨가 64.5 g QE/kg DM로 가장 높은 결과를 나타내었다. HPLC를 통하여 이미 잘 알려진 항산화제인 caffeic acid와 rosmarinic acid의 함유량을 측정한 결과, caffeic acid는 보라들깨에서, rosmarinic acid는 동글2호에서 가장 높은 함유량을 나타내었다. 즉, 이 종합적인 비교를 통하여 항산화능력과 생리활성물질...


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