자료유형
발행기관
- 대한신경정신의학회(64)
- 대한생리학회-대한약리학회(35)
- 대한약리학회(14)
- 대한수의학회(5)
- 대한약학회(4)
- 대한화학회(4)
- 한국미생물생명공학회(3)
- 한국생약학회(3)
- 대한생리학회(2)
- 대한화장품학회(2)
- 한국생명과학회(2)
- 한국생물공학회(2)
- 한국식물병리학회(2)
- 한국음악치료학회(2)
- 경락경혈학회(1)
- 대한생물정신의학회(1)
- 대한신경계작업치료학회(1)
- 대한임상약리학회(1)
- 대한침구학회(1)
- 대한한방안이비인후피부과학회(1)
- 생화학분자생물학회(1)
- 한국곤충학회(1)
- 한국버섯학회(1)
- 한국수산과학회(1)
- 한국식품과학회(1)
- 한국식품저장유통학회(1)
- 한국원예학회(1)
- 한국응용약물학회(1)
- 한국자원식물학회(1)
- 한국종교교육학회(1)
- 한국탄소학회(1)
간행물
- 신경정신의학(64)
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(35)
- 대한약리학잡지(14)
- ARCHIVES OF PHARMACAL RESEARCH : A PUBLICATION OF THE PHARMACEUTICAL SOCIETY OF KOREA(3)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(3)
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY(2)
- JOURNAL OF VETERINARY SCIENCE(2)
- NATURAL PRODUCT SCIENCES(2)
- THE PLANT PATHOLOGY JOURNAL (2)
- 대한생리학회지(2)
- 대한화장품학회지(2)
- 대한화학회지(2)
- 생명과학회지(2)
- 한국생물공학회지(2)
- 한국음악치료학회지(2)
- CARBON LETTERS(1)
- JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY(1)
- KOREAN JOURNAL OF ENTOMOLOGY(1)
- THE JOURNAL OF APPLIED PHARMACOLOGY : THE OFFICIAL JOURNAL OF THE KOREAN SOCIETY OF APPLIED PHARMACO(1)
- 경락경혈학회지= KOREAN JOURNAL OF ACUPUNCTURE(1)
- 대한침구학회지= THE JOURNAL OF KOREAN ACUPUNCTURE & MOXIBUSTION SOCIETY(1)
- 산업미생물학회지(1)
- 생물정신의학(1)
- 생약학회지(1)
- 약학회지(1)
- 원예과학기술지(1)
- 임상약리학회지= THE JOURNAL OF KOREAN SOCIETY FOR CLINICAL PHARMACOLOGY AND THERAPEUTICS(1)
- 재활치료과학(1)
- 종교교육학연구(1)
- 한국미생물-생명공학회지(1)
- 한국버섯학회지(1)
- 한국생화학회지(1)
- 한국식품과학회지(1)
- 한국식품저장유통학회지(1)
- 한국양식학회지(1)
- 한국자원식물학회지(1)
- 한방안이비인후피부과학회지(1)
전체 선택해제
총 161건 검색
본문검색 결과만 보기
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Antioxidant Effects of Serotonin and L-DOPA on Oxidative Damages of Brain Synaptosomes
SangSooHam, DongHyunKim, SukHaLee, YunSangKim, ChungSooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 4 147-155 (9 pages)
EDTA, H2O2 and ascorbate or xanthine and xanthine oxidase was significantly decreased by serotonin and L-DOPA (1 mM). Equal concentrations of serotonin and L-DOPA restored synaptosomal Ca2 uptake decreased by Fe2 and ascorbate, which is responsible for SOD and catalase. Protective effects of serotonin and L-DOPA on brain synaptosomes may be attributed to their removing action on reactive oxidants, hydroxyl radicals and probably iron-oxygen complex, without chelating action on iron. -
분광광도계를 이용한 L-tyrosine과 L-DOPA 혼합물의 분석방법
김지현, 유영제 한국생물공학회 한국생물공학회지 4 Pages
한국생물공학회 한국생물공학회지 1990, Vol.5 No.2 191-194 (4 pages)
Tytosine은 방향족 아미노산이고, L-DOPA는 orth위치에 수산화기를 하나 더 가지는 tyrosine유도체이다. L-DOPA는 효소에 의하여 tyrosine으로부터 전환되어 생성할 수 있는데 반응액에서 두 물질을 분리, 분석하는 것은 상당히 어렵다. 본 논문에서는 두 아미노산 혼합물을 UV/VIS spetrophotermeter를 이용하여 동정함으로써 두 물질이 구분되는 두 파장을 결정하였고 두 파장에서 혼합물의 흡광도를 측정함으로써 농도를 정량하는 분석 system을 확립하였다. 이 방법은 사료에 아무런 전처리가 필요없으므로 손쉽고 간단하게 분석에... -
Production of L-DOPA by Thermostable Tyrosine Phenol-lyase of a Thermophilic Symbiobacterium Species Overexpressed in Recombinant Escherichia coli
Lee. Seung-Goo, Ro. Hyeon-Su, Hong. Seung-Pyo, Kim. Eun-Hwa, Sung. Moon-Hee 한국미생물생명공학회 Journal of microbiology and biotechnology 5 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 1996, Vol.6 No.2 98-102 (5 pages)
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Fluphenazine , Lithium 및 L- dopa 가 가토 혈중 주정농도에 미치는 영향에 관한 실험적 연구
대한신경정신의학회 신경정신의학 1974, 제 13권 제 4호 12 466-474 (9 pages)
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보조 형광증가제를 이용한 L-Dopa의 형광분광법적 정량
이상학, 안정미, Lee. Sang Hak, Ahn. Jung Mi 대한화학회 대한화학회지 6 Pages
대한화학회 대한화학회지 2000, Vol.44 No.6 541-546 (6 pages)
및 방출파장의 방출세기에 대한 영향을 조사하였다. 보조 형광증가제로서 Lu(III) 이온을 첨가하였을때 Tb(III) 이온의 방출세기가 현저히 증가함을 관찰하였고, L-dopa의 검출한계를 낮출 수 있었다. 보조 형광증가제를 첨가하지 않았을 경우에 L-dopa 검정곡선의 직선감응범위는 들뜸파장, pH 및 Tb(Ⅲ) 이온의 농도가 각각 300 nm, 8.0 및 $1.0{ imes}10^{-4}$ M였을때, $5.0{ imes}10^{-7}$ M~$1.0{ imes}10^{-4}$ M였다. 이 조건에서의 검출한계는 $4.0{ imes}10^{-8}$ M였다. 보조 형광증가제를 첨가하였을 경우에는 들뜸파장, pH,... -
Chelidonine이 PC12 세포내의 L-DOPA-유도 세포독성에 미치는 영향
김유미, 이재준, 김춘매, 양유정, 강민희, 이명구, Kim. Yu-Mi, Lee. Jae-Joon, Jin. Chun-Mei, Yang. Yoo-Jung, Kang. Min-Hee, Lee. Myung-Koo 한국생약학회 생약학회지 4 Pages
한국생약학회 생약학회지 2003, Vol.34 No.3 242-245 (4 pages)
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Inhibition of L-DOPA-Induced Increase in Dopamine Content by $(1R,9S)-{eta}-Hydrastine$ Hydrochloride in PC12 cells
Yin. Shou-Yu, Lee. Jae-Joon, Kim. Yu-Mi, Jin. Chun-Mei, Yang. Yoo-Jung, Kang. Min-Hee, Lee. Myung-Koo 한국생약학회 Natural product sciences 5 Pages
한국생약학회 Natural product sciences 2004, Vol.10 No.3 119-123 (5 pages)
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니켈(II)-거대고리 착물로 변성된 유리질 탄소 전극을 이용한 L-Dopa의 전기화학적 정량
이선용, 조형화, 김호식, 배준웅, Yi. Seon-Yong, Cho. Hyung-Hwa, Kim. Ho-Sik, Bae. Zun-Ung 대한화학회 대한화학회지 9 Pages
대한화학회 대한화학회지 2005, Vol.49 No.1 47-55 (9 pages)
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Liriodenine Inhibits Dopamine Biosynthesis and L-DOPA-Induced Dopamine Content in PC12 Cells
Jin. Chun-Mei, Lee. Jae-Joon, Yang. Yoo-Jung, Kim. Yu-Mi, Kim. Young-Kyoon, Ryu. Shi-Yong, Lee. Myung-Koo 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 7 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2007, Vol.30 No.8 984-990 (7 pages)
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Effects of Tributyltin Acetate on Dopamine Biosynthesis and L-DOPA-Induced Cytotoxicity in PC12 Cells
Kim. Yu-Mi, Lee. Jae-Joon, Park. Seung-Kook, Lim. Sung-Cil, Hwang. Bang-Yeon, Lee. Chong-Kil, Lee. Myung-Koo 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 8 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2007, Vol.30 No.7 858-865 (8 pages)
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Effects of Tributyltin Chloride on L-DOPA-Induced Cytotoxicity in PC12 Cells
Lee. Jae-Joon, Kim. Yu-Mi, Park. Seung-Kook, Lee. Myung-Koo 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 6 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2006, Vol.29 No.8 645-650 (6 pages)
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재조합 대장균에서 과발현된 Citorbacter Freundii KCTC2006 유래의 ${eta}$-Tyrosinase를 이용한 3,4-Dihydroxyphenyl-L-alannine의 생산
이승구, 노현수, 홍승표, 이규종, 왕지원, 태동년, 엄기남, 방상구, 김영준, 성문희, Lee. Seung-Goo, Ro. Hyeon-Su, Hong. Seung-Pyo, Lee. Kyu-Jong, Wang. Ji-Won, Tae. Dong-Nyeon, U 한국미생물생명공학회 산업미생물학회지 6 Pages
한국미생물생명공학회 산업미생물학회지 1996, Vol.24 No.1 44-49 (6 pages)
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Ethyl linoleate inhibits α-MSH-induced melanogenesis through Akt/GSK3β/β-catenin signal pathway
Gyeong-AKoSomiKimCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 6 53-61 (9 pages)
Ethyl linoleate is an unsaturated fatty acid used in many cosmetics for its various attributes, such as antibacterial and anti-inflammatory properties and clinically proven to be an effective anti-acne agent. In this study, we investigated the effect of ethyl linoleate on the melanogenesis and the mechanism underlying its action on melanogenesis in B16F10 murine melanoma cells. Our results revealed that ethyl linoleate significantly inhibited melanin content and intracellular tyrosinase activity... -
ERK Activation by Fucoidan Leads to Inhibition of Melanogenesis in Mel-Ab Cells
YuSeokSong, MarieCarmelBalcos, Hye-YoungYun, KwangJinBaek, NyounSooKwon, Myo-KyoungKim, Dong-SeokKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 5 29-34 (6 pages)
Fucoidan, a fucose-rich sulfated polysaccharide derived from brown seaweed in the class Phaeo-phyceae, has been widely studied for its possible health benefits. However, the potential of fucoidan as a possible treatment for hyperpigmentation is not fully understood. This study investigated the effects of fucoidan on melanogenesis and related signaling pathways using Mel-Ab cells. Fucoidan significantly decreased melanin content. While fucoidan treatment decreased tyrosinase activity, it did not... -
Differential Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on Motor Behavior and Dopamine Levels at Brain Regions in Three Different Mouse Strains
Keun-SungLee, Jin-KooLee, Hyung-GunKim, HakRimKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 13 89-97 (9 pages)
Developing an animal model for a specific disease is very important in the understanding of the underlying mechanism of the disease and allows testing of newly developed new drugs before human application. However, which of the plethora of experimental animal species to use in model development can be perplexing. Administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a very well known method to induce the symptoms of Parkinson's disease in mice. But, there is very limited... -
Lithium-induced Increase of Synaptosomal Uptake of Norepinephrine in Rat Brain
Young-WukCho, Seung-HoHan, Chang-JuKim, Byung-IlMin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 2 127-133 (7 pages)
Lithium remains the most widely used therapeutic agent for bipolar affective disorder, particularly mania. Although many investigators have studied the effects of lithium on abnormalities in monoamine neurotransmitter as a pathophysiological basis of affective disorder, the action mechanism of lithium ion remains still unknown. To explore the action mechanism of lithium in the brain, we examined the effects of lithium on the extrasynaptosomal concentrations of catecholamines and their...
