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Pak1/LIMK1/Cofilin Pathway Contributes to Tumor Migration and Invasion in Human Non-Small Cell Lung Carcinomas and Cell Lines
InseokJang, ByeongTakJeon, EunAeJeong, Eun-JinKim, DawonKang, JongSilLee, BaekGeunJeong, JinHyunKim6, BongHoiChoi6, JungEunLee, JongWooKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.3 2 159-165 (7 pages)
of non-small cell lung carcinoma (NSCLC). Although both SCCs and ACs have been characterized histologically and clinically, the precise mechanisms underlying their migration and invasion are not yet known. Here, we address the involvement in NSCLC of the p21-associated kinase1 (Pak1)/LIM kinase1 (LIMK1)/cofilin pathway, which recently has been reported to play a critical role in tumor migration and invasion. The Pak1/LIMK1/cofilin pathway was evaluated in tumors from SCC (n=35) and AC (n=35)... -
Inhibition of Tumor Invasion and Metastasis by Calcium Spirulan(Ca-SP), a Novel Sulfated Polysaccharide Derived from a Blue-Green Alga Spirulina Platensis
Saiki. Ikuo, Murata. Jun, Fujii. Hideki, Kato. Toshimitsu 한국영양학회 Nutritional sciences 7 Pages
한국영양학회 Nutritional sciences 2004, Vol.7 No.3 144-150 (7 pages)
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Melittin Suppresses PMA-Induced Tumor Cell Invasion by Inhibiting NF-${kappa}$B and AP-1-Dependent MMP-9 Expression
Park. Jung-Hyun, Jeong. Yun-Jeong, Park. Kwan-Kyu, Cho. Hyun-Ji, Chung. Il-Kyung, Min. Kwan-Sik, Kim. Mi-Hyun, Lee. Kwang-Gill, Yeo. Joo 한국분자세포생물학회 Molecules and cells 7 Pages
한국분자세포생물학회 Molecules and cells 2010, Vol.29 No.2 209-215 (7 pages)
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Role of Transforming Growth Factor-β in Tumor Invasion and Metastasis
Kim. Eun-Sook, Moon. Aree 한국독성학회 Journal of toxicology and public health : an official journal of the Korean Society of Toxicology 9 Pages
한국독성학회 Journal of toxicology and public health : an official journal of the Korean Society of Toxicology 2007, Vol.23 No.3 197-205 (9 pages)
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Clinicopathological Significance of Lymphangiogenesis and Tumor Lymphovascular Invasion in Indonesian Breast Cancers
Widodo. Irianiwati, Ferronika. Paranita, Harijadi. Ahmad, Triningsih. F.X. Ediati, Utoro. Totok, Soeripto. Soeripto 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.2 997-1001 (5 pages)
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Epigallocatechin-3-gallate inhibits paracrine and autocrine hepatocyte growth factor/scatter factor-induced tumor cell migration and invasion
Kwak. In-Hae, Shin. Yun-Hye, Kim. Myeong-Deok, Cha. Hyun-Young, Nam. Hyun-Ja, Lee. Bok-Soon, Chaudhary. S.C., Pai. Ki-Soo, Lee. Jae-Ho 생화학분자생물학회 Experimental & molecular medicine : EMM 10 Pages
생화학분자생물학회 Experimental & molecular medicine : EMM 2011, Vol.43 No.2 111-120 (10 pages)
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A Method to Quantify Breast MRI for Predicting Tumor Invasion in Patients with Preoperative Biopsy- Proven Ductal Carcinoma in Situ (DCIS)
고명수, 김성헌, 강봉주, 최병길, 송병주, 차은숙, 김인성, Ko. Myung-Su, Kim. Sung Hun, Kang. Bong Joo, Choi. Byung Gil, Song. Byung Joo, Cha. Eun Suk, Kiraly. Atill 대한자기공명의과학회 대한자기공명의과학회지 10 Pages
대한자기공명의과학회 대한자기공명의과학회지 2013, Vol.17 No.2 73-82 (10 pages)
목적: 수술전 관상내피암으로 진단된 환자에서 침윤성 유방암을 예측하는 정량적 파라미터를 알아보고자 한다. 대상과 방법: 2009년 1월부터 2010년 3월까지, 조직생검상 관상피내암으로 진단된 41명 환자의 42 자기공명영상을 분석하였다. 정량적 파라미터로는 초기조영증강정도, 최대조영증강 정도, 초기에 빠르면서 최대 조영증강을 보인 시점, 조영증강정도, 동맥기 조영증강비율, 겉보기확산계수, 병변의 지름과 용적을 분석하였다. 정량적 파라미터와 침윤성과 연관관계를 알기 위해 일변량 분석과 다변량 분석을 시행하였다. 결과:... -
A Case Report of Malignant Localized Fibrous Tumor of the Pleura with Chest Wall Invasion
최석진, 윤혜경, Choe. Seok-Jin, Yun. Hye-Gyeong 대한영상의학회 대한방사선의학회지 4 Pages
대한영상의학회 대한방사선의학회지 2003, Vol.49 No.5 405-408 (4 pages)
국한성섬유종양은흉막에서기원한종양으로천천히성장하며경계가좋고거대한크기를특징으로한다.양성국한성 섬유종양에대한 여러가지 방사선 소견에 대한보고가있으나,흉벽을 침범하는 악성국한성섬유종양에 대한 방사선학적 소견은 아직 보고 되지 않았다.저자들은 수술로서 확진된 흉벽을 침범하는 악성 국한성 섬유종양을 경험하였기에문헌고찰과함께보고한다. -
CD204-positive tumor-associated macrophages are related with malignant, high–grade, and hormone receptor-negative canine mammary gland tumors
Byung-joon Seung, Ha-young Lim, Seung-hee Cho, Soo-hyeon Kim, Jung-hyang Sur 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 53 228-228 (1 pages)
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In vitro treatment of lipopolysaccharide increases invasion of Pasteurella multocida serotype B:2 into bovine aortic endothelial cells
Seng Kar Yap, Zunita Zakaria, Siti Sarah Othman, Abdul Rahman Omar 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 7 207-215 (9 pages)
septicemia in cattle and buffalo. The invasion mechanism of the bacterium when invading the bloodstream is unclear. This study aimed to characterize the effects of immunomodulatory molecules, namely dexamethasone and lipopolysaccharide, on the invasion efficiency of P. multocida serotype B:2 toward bovine aortic endothelial cells (BAECs) and the involvement of actin microfilaments in the invasion mechanism. The results imply that treatment of BAECs with lipopolysaccharide at 100 ng/mL for 24 h... -
Establishment of a canine mammary gland tumor cell line and characterization of its miRNA expression
Tomohiro Osaki, Yuji Sunden, Akihiko Sugiyama, Kazuo Azuma, Yusuke Murahata, Takeshi Tsuka, Norihiko Ito, Tomohiro Imagawa, Yosh 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 3호 16 385-390 (6 pages)
tumor formed in each NOD.CB17-Prkdc/J mouse at the site of subcutaneous SNP cell injection. SNP cells are characterized by proliferation in a tubulopapillary pattern and are vimentin positive. Moreover, we examined miRNA expression in the cultured cells and found that the expression values of miRNA-143 and miRNA-138a showed the greatest increase and decrease, respectively, of all miRNAs observed, indicating that these miRNAs might play a significant role in the malignancy of SNP cells. Overall,... -
Downregulation of cellular prion protein inhibited the proliferation and invasion and induced apoptosis of Marek’s disease virus-transformed avian T cells
Xuerui Wan, Runxia Yang, Guilin Liu, Manling Zhu, Tianliang Zhang, Lei Liu, Run Wu* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 2호 6 171-178 (8 pages)
of chPrPinhibits proliferation, invasion, and migration, and induces G1 cell cycle phase arrest and apoptosis of MSB1-SiRNA-3 cells compared with Marek’s disease virus-transformed avian T cells (MSB1) and negative control cells. To the best of our knowledge, the present study provides the first evidence supporting the positive correlation between the expression level of chPrP and the proliferation, migration, and invasion ability of MSB1 cells, but appears to protect MSB1 cells from apoptosis,... -
The potential role of COX-2 in cancer stem cell-mediated canine mammary tumor initiation: an immunohistochemical study
Jian Huang, Di Zhang, Fuqiang Xie, Degui Lin 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 13 225-231 (7 pages)
effect on CSC-mediated tumor initiation in primary canine mammary tissues and tumorsphere models using immunohistochemistry. Patterns of COX-2, CD44, octamer-binding transcription factor (Oct)-3/4, and epidermal growth factor receptor (EGFR) expression were examined in malignant mammary tumor (MMT) samples and analyzed in terms of clinicopathological characteristics. COX-2 and Oct-3/4 expression was higher in MMTs compared to other histological samples with heterogeneous patterns. In MMTs, COX-2... -
Malignant mixed tumor in the salivary gland of a cat
Heejaung Kim, Munekazu Nakaichi, Kazuhito Itamoto, Yasuho Taura 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 3호 15 331-334 (4 pages)
malignant mixed tumor, also known as a carcinosarcoma, in the salivary gland is very rare. Such tumors, which are typically aggressive, are characterized by the presence of carcinomatous and sarcomatous components. A 9-year-old neutered female domestic short-haired cat presented with swelling in the right mandibular lesion that had rapidly enlarged over the previous 3 weeks. Physical examination revealed a large, fluctuated and painless subcutaneous swelling that was associated with a firm mass.... -
Ultrasonographic assessment of transitional cell carcinoma of the urinary bladder in dogs: a perspective of tumor size change
Seungji Kim , Yongbaek Kim , Wanhee Kim , Mincheol Choi , Junghee Yoon 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 4 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2017, 제 57권 제 3호 10 205-208 (4 pages)
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Case Report : Primary renal fibrosarcoma with local invasion into the mesenteric membrane of a mongrel dog
Hyun Ah Park , Chang Woo Jeong , Gui Soo Kim , Han Jun Kim , Sun Hee Do , Hee Myung Park 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 5 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2015, 제 55권 제 1호 11 65-69 (5 pages)
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Extracellular acidity enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis via DR5 in gastric cancer cells
Ran Hong, Song Iy Han 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 5 513-523 (11 pages)
The tumor microenvironment greatly influences cancer cell characteristics, and acidic extracellular pH has been implicated as an essential factor in tumor malignancy and the induction of drug resistance. Here, we examined the characteristics of gastric carcinoma (GC) cells under conditions of extracellular acidity and attempted to identify a means of enhancing treatment efficacy. Acidic conditions caused several changes in GC cells adversely affecting chemotherapeutic treatment. Extracellular...


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