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전체 선택해제
총 687건 검색
본문검색 결과만 보기
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Platelet rich plasma improves dermal therapeutic effect of mesenchymal stem cells via enhancing angiogenesis
Hyun-wook Myung, Se-hwan Shim, Hyo-sun Jang, Jae Kyung Myung, Won Suk Jang, Sun Joo Lee, Hye-won Kim, Janet Lee, Ji Hoon Kang, Ju Hui Par 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 192 315-316 (2 pages)
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Effect of autologous platelet-rich plasma application on cutaneous wound healing in dogs
Cho-Hee Jee, Na-Young Eom, Hyo-Mi Jang, Hae-Won Jung, Eul-Soo Choi, Jin-Hee Won, Il-Hwa Hong, Byeong-Teck Kang, Dong Wook Jeong, 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 1호 10 79-87 (9 pages)
This study was conducted to identify the effectiveness of platelet-rich plasma (PRP) and efficacy of intralesional injection as a method of application to acute cutaneous wounds in dogs. Healthy adult beagles (n = 3) were used in this study. Autologous PRP was separated from anticoagulant treated whole blood in three dogs. Cutaneous wounds were created and then treated by intralesional injection of PRP in the experimental group, while they were treated with saline in the control group on days 0,... -
Osteogenic potential of mesenchymal cells derived from canine umbilical cord matrix co-cultured with platelet-rich plasma and demineralized bone matrix
Talita F.B. Souza, Silmara S. Sakamoto, Gabriel T.N.M. Ferreira, Roberto Gameiro, Marcia Marinho, Alexandre L. de Andrade, Terez 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 17 381-384 (4 pages)
or not supplemented with platelet rich plasma (PRP) and demineralized bone matrix (DBM) to verify osteogenic differentiation. Osteoblastic differentiation followed by mineralized bone matrix production was found to be significantly higher (p ＜ 0.05) when MSCs were associated with PRP/DBM in culture after 14–21-days of induction. Osteopontin and osteocalcin gene expression were significantly superior (p ＜ 0.05) under the same culture conditions after 21 days of observation. In... -
Application of vincristine-loaded platelet therapy in three dogs with refractory immune-mediated thrombocytopenia
Hyung-Jin Park, Ja-Won Kim, Kun-Ho Song, Kyoung-Won Seo 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 17 127-130 (4 pages)
Three dogs presented with refractory immune-mediated thrombocytopenia (IMT). All patients failed to respond to prednisone, which is considered a mainstay of immunosuppressive therapy. Vincristine-loaded platelets (VLPs), which act selectively on mononuclear phagocytes,were introduced. After the VLPs were transfused, two dogs responded quickly withimproved clinical signs while the third dogwith recurrent IMT was euthanized due to its deteriorating condition. This case report... -
Oxidative response of neutrophils to platelet-activating factor is altered during acute ruminal acidosis induced by oligofructose in heifers
Claudia Concha, María Daniella Carretta, Pablo Alarcón, Ivan Conejeros, Diego Gallardo, Alejandra Isabel H 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 2호 7 217-224 (8 pages)
augmented during acute ruminal acidosis, reduces platelet activating factor (PAF)-induced ROS production and L-selectin shedding in bovine neutrophils in vitro. This study was conducted to investigate whether acute ruminal acidosis induced by acute oligofructose overload in heifers interferes with ROS production and L-selectin shedding in blood neutrophils. Blood neutrophils and plasma were obtained by jugular venipuncture, while ruminal samples were collected using rumenocentesis. Lactic acid... -
Water soluble tomato concentrate regulates platelet function via the mitogen-activated protein kinase pathway
Dahye Jeong , Muhammad Irfan , Evelyn Saba , Sung Dae Kim , Seung Hyung Kim , Man Hee Rhee 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 8 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2016, 제 56권 제 2호 2 67-74 (8 pages)
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Murrayafoline A Induces a G0/G1-Phase Arrest in Platelet-Derived Growth Factor-Stimulated Vascular Smooth Muscle Cells
Joo-HuiHan, YohanKim, Sang-HyukJung, Jung-JinLee, Hyun-SooPark, Gyu-YongSong, NguyenManhCuong, YoungHoKim, Chang-SeonMyung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.5 4 421-426 (6 pages)
The increased potential for vascular smooth muscle cell (VSMC) growth is a key abnormality in the development of atherosclerosis and post-angioplasty restenosis. Abnormally high activity of plate-let-derived growth factor (PDGF) is believed to play a central role in the etiology of these pathophy-siological situations. Here, we investigated the anti-proliferative effects and possible mechanism(s) of murrayafoline A, a carbazole alkaloid isolated from Glycosmis stenocarpa Guillamin (Rutaceae), on... -
Myocardial Protection by Recombinant Soluble P-selectin Glycoprotein Ligand-1 Suppression of Neutrophil and Platelet Interaction Following Ischemia and Reperfusion
SangSooHam, YoonYoungJang, JinHoSong, HyangMiLee, KwangJoonKim, JunSikHong, YongKyooShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.6 10 507-513 (7 pages)
as PMN accumulation and P-selectin expression were markedly attenuated by a recombinant soluble PSGL-1 which inhibits selectin mediated cell adhesion. These results provide evidence that platelets and PMNs act synergistically in provoking post-reperfusion cardiac dysfunction, and that this may be largely due to cell to cell interactions mediated by P-selectin. These results also demonstrate that a recombinant soluble PSGL-1 reduces myocardial reperfusion injury by platelet and PMNs interaction. -
Increase of Intracellular Ca2+ Concentration by Vibrio Vulnificus Cytolysin in Rat Platelets; Triggering Mechanism of Platelet Cytolysis
JinBongParkSooWanChae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 10 199-205 (7 pages)
concentration-dependent manner. In the presence of V. vulnificus cytolysin (3 HU/ml), lactate dehydrogenase (LDH) activity was increased from 1.3⁑0.4% of control to 64.3⁑3.4% in platelet suspension buffer. In Ca2-free platelet suspension buffer, however, V. vulnificus cytolysin did not induce [Ca2]i increase and LDH release. Addition of EGTA (2 mM) to suspension buffer after the initial Ca2 influx reversed [Ca2]i to the control level. However, a Ca2... -
Effect of the Inhibition of Platelet Activating Factor on Oxidative Lung Injury Induced by Interleukin-1α
YoungManLeeYoon-YubPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 10 479-491 (13 pages)
platelet activating factor (1-0-alkyl-2-acetyl-sn- glycero-3-phosphocholine, PAF) was investigated during acute lung injury induced by interleukin- 1α (IL-1) in rats. An insufflation of IL-1 into the rat's trachea increased the acetyltransferase activity in the lung and the increase of PAF content was followed. As evidences of acute lung injury by neutrophilic respiratory burst, lung leak index, myeloperoxidase activity, numbers of neutrophils in the bronchoalveolar lavage fluid, neutrophilic... -
Platelet-Activating Factor Enhances Interleukin-1 Activity by Alveolar Macrophages Inhibition by PAF Specific Receptor Antagonists
JiheeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 10 201-208 (8 pages)
It is becoming increasingly clear that the inflammatory reaction can be ascribed to a complex array of mediators generated and released from activated phagocytes. In this study, the effect of PAF on interleukin-1(IL-1) activity by rat alveolar macrophages(AM) was examined using thymocyte proliferation assay in the supernate of sample obtained after 24 hr culture. When AM were cultured with PAF alone, no change in IL-1 activity was observed. However, the combined addition of PAF and muramyl... -
Platelet Activating Factor에 의한 대식세포의 활성화에 있어서 칼슘과 Protein Kinase C의 역할
이정수(Chung-Soo Lee), 김영준(Young-Jun Kim), 신용규(Yong-Kyoo Shin), 이광수(Kwang-Soo Lee) 대한약리학회 대한약리학잡지 14 Pages
대한약리학회 대한약리학잡지 1993, 제 29권 제 1호 11 107-120 (14 pages)
입자 또는 용해성 자극 물질들은 칼슘 이동의 변화와 protein kinase C의 활성화를 초래하여 식 세포의 반응을 자극하는 것으로 추정하고 있다. 이에 비해서 protein kinase C가 활성화되면 호중구에서 agonist에 의한 세포 칼슘 농도의 증가가 억제된다고 보고하고 있다. PAF는 peritoneal macrophage에서 세포내 칼슘 농도를 용량에 따라 증가시켰으며 칼슘의 유출이 동반되었다. PAF에 의한 세포내 칼슘 농도의 증가는 TMB-8, verapamil과 TTX의 영향을 받지 않았다. TEA는 PAF에 의한 세포내 칼슘 이동을 자극하였으며 세포내 칼슘... -
Effects of Platelet-Activating Factor on Tumor Necrosis Factor-α Production by Muramyl Dipeptide- or Silica-Stimulated Alveolar Macrophages
Lee, Ji-Hee, Hah, Jong-Sik 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 1호 8 77-84 (8 pages)
Platelet-activating factor(PAF) is a phospholipid mediator of pulmonary inflammation, and immunologic reaction. In this study, the role of PAF on tumor necrosis factor(TNF-α) production by rat alveolar macrophages(AM) was examined. When PAF (10-12 ~ 10-16 M) alone was added to AM culture, (TNF-α) production was not significantly increased above the resting level. In contrast, the combined addition of PAF (10-6 M) and muramyl dipeptide(MDP) (1.0 μg\ml) to AM cultures markedly enhanced (TNF-α)... -
Platelet-Activating Factor Potentiates the Activity of Respiratory Burst and Interleukin-1 in Rat Alveolar Macrophages
Lee, Ji-Hee 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 7 251-258 (8 pages)
The objective of the present study was to test the effect of platelet-activating factor (PAF) on rat alveolar macrophages. PAF alone did not stimulate superoxide secretion from alveolar macrophages. However, PAF (10-5 M) significantly enhanced phagocytic activator zymosan-induced superoxide secretion from alveolar macrophages. This enhancement of PAF plus zymosan was 30% above the sum of the separate effects of PAF and zymosan. Similarly, PAF 1.3 X (10-5 M) was not a direct stimulant of alveolar... -
A Study of Mechanism Involved in Cadmium-induced Platelet Aggregation
송철수(Cheul Soo Song), 홍기환(Ki Whan Hong) 대한약리학회 대한약리학잡지 6 Pages
대한약리학회 대한약리학잡지 1984, 제 20권 제 1호 5 41-46 (6 pages)
Furthermore, the inhibition of 6-keto-prostaglandin F1α, production in Cd-treated aorta ring was inversely related to the enhancement of platelet aggregation. These results suggest that Cd not only inhibits prostacyclin synthesis in the arterial endothelium, but also stimulates the platelet aggregation by enhancing thromboxane AZ production. These findings are assumed to support the evidence of an effect of Cd toxicity on the vascular wall and platelet function in raising arteriall pressure. -
Activation of Platelet Rich Plasma by Soluble Canine Small Intestinal Submucosa Gel and Bovine Thrombin
이아진, 이창선, 김현, 정다정, 도선희, 김휘율, Lee. A-Jin, Lee. Changsun, Kim. Hyun, Chung. Dai-Jung, Do. Sun Hee, Kim. Hwi-Yool 한국임상수의학회 Journal of veterinary clinics 5 Pages
한국임상수의학회 Journal of veterinary clinics 2014, Vol.31 No.3 170-174 (5 pages)
본 연구는 개 소장점막하 조직을 겔화시킨 것과 일반적으로 사용하는 소 트롬빈, 그리고 이 두 가지 요소를 혼합한 것을 혈소판풍부혈장의 활성화 인자로 적용하여, 혈소판에서 분비되는 성장인자를 7일간 in vitro 실험을 실시하였다. 또한 전자현미경으로 각 그룹 별 샘플의 표면을 관찰하여, 측정한 성장인자와의 상관관계를 연구하였다. 그 결과, 그룹별로 유의적인 차이는 존재하지 않았지만, 성장인자인 (TGF)-${eta}1$이 가장 많이 분비된 그룹은 혈소판풍부혈장을 개 소장점막하조직 겔로 활성화시켰을 때였다. 본 연구 결과를... -
Terpene-Strengthened Ginkgo biloba Extract as a Platelet-Activating Factor Antagonist
Quan. Zhe-Jiu, Moon. Tae-Chul, Yang. Ju-Hye, Chang. Hyeun-Wook, Park. Young-Hyun, Kim. Young-Ha, Lee. Kyung-Hee, Chi. Yeon-Sook, Lim. Hy 한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 6 Pages
한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 2006, Vol.14 No.3 160-165 (6 pages)
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In Vitro Effect of Aspalatone on Platelet Aggregation and Thromboxane Production in Human Platelet Rich Plasma
Suh. Dae-Yeon, Han. Byung-Hoon 한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 5 Pages
한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 1996, Vol.4 No.2 122-126 (5 pages)
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Spinach Saponin-Enriched Fraction Inhibits Platelet Aggregation in cAMP- and cGMP-Dependent Manner by Decreasing TXA2 Production and Blood Coagulation
Cho. Hyun-Jeong, Choi. Sun-A, Kim. Chun-Gyu, Jung. Tae-Sung, Hong. Jeong-Hwa, Rhee. Man-Hee, Park. Hye-Jin, Park. Hwa-Jin 한국응용약물학회 Biomolecules & therapeutics 6 Pages
한국응용약물학회 Biomolecules & therapeutics 2011, Vol.19 No.2 218-223 (6 pages)
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Direct simulations of orientational dispersion of platelet particles in a viscoelastic fluid subjected to a partial drag flow for effective coloring of polymers
Hwang. Wook-Ryol, Kim. Worl-Yong, Lee. Eon-Seok, Park. Chung-Hae 한국유변학회 Korea-Australia rheology journal 9 Pages
한국유변학회 Korea-Australia rheology journal 2011, Vol.23 No.3 173-181 (9 pages)
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Effects of green tea or $Sasa$ $quelpaertensis$ bamboo leaves on plasma and liver lipids, erythrocyte Na efflux, and platelet aggregation in ovariectomized rats
Ryou. Sung-Hee, Kang. Min-Sook, Kim. Kyu-Il, Kang. Young-Hee, Kang. Jung-Sook 한국영양학회 Nutrition research and practice 7 Pages
한국영양학회 Nutrition research and practice 2012, Vol.6 No.2 106-112 (7 pages)
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Effect of coenzyme Q10 and Ardisia japonica Blume on plasma and liver lipids, platelet aggregation, and erythrocyte Na efflux channels in simvastatin-treated guinea pigs
Kang. Min Sook, Yang. Hun Mo, Kang. Ja Young, Ryou. Sung Hee, Kang. Jung Sook 한국영양학회 Nutrition research and practice 7 Pages
한국영양학회 Nutrition research and practice 2012, Vol.6 No.5 414-420 (7 pages)
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Effect of onion and beet on plasma and liver lipids, platelet aggregation, and erythrocyte Na efflux in simvastatin treated hypercholesterolmic rats
Kim. Jung-Lye, Chae. In-Sook, Kang. Young-Hee, Kang. Jung-Sook 한국영양학회 Nutrition research and practice 7 Pages
한국영양학회 Nutrition research and practice 2008, Vol.2 No.4 211-217 (7 pages)
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Effects of taurine on plasma and liver lipids, erythrocyte ouabain sensitive Na efflux and platelet aggregation in Sprague Dawley rats
Park. In-Sun, Kang. Young-Hee, Kang. Jung-Sook 한국영양학회 Nutrition research and practice 6 Pages
한국영양학회 Nutrition research and practice 2007, Vol.1 No.3 200-205 (6 pages)
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Effect of Coenzyme Q10 and green tea on plasma and liver lipids, platelet aggregation, TBARS production and erythrocyte Na leak in simvastatin treated hypercholesterolmic rats
Kim. Yang-Hee, Moon. Young-In, Kang. Young-Hee, Kang. Jung-Sook 한국영양학회 Nutrition research and practice 7 Pages
한국영양학회 Nutrition research and practice 2007, Vol.1 No.4 298-304 (7 pages)
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Effects of Green Tea Catechin on Platelet Phospholipase $A_{2}$ Activity and the Liver Antioxidative Defense System in Streptozotocin-induced Diabetic Rats
Yang. Jeong-Ah, Rhee. Soon-Jae 한국식품영양과학회 Journal of food science and nutrition 6 Pages
한국식품영양과학회 Journal of food science and nutrition 2000, Vol.5 No.4 213-218 (6 pages)
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Extracts from Rhizopus oryzae KSD-815 of Korean Traditional Nuruk Confer the Potential to Inhibit Hypertension, Platelet Aggregation, and Cancer Metastasis in vitro
Lee. Sang-Jin, Bae. Hyun-Jin, Ryu. Ji-Yeon, Lee. Dae-Young, Kim. Gye-Won, Baek. Na-Min, Kwon. Moo-Sik, Hong. Sung-Youl 한국식품과학회 Food science and biotechnology 7 Pages
한국식품과학회 Food science and biotechnology 2009, Vol.18 No.6 1423-1429 (7 pages)
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Inhibitory Effects of Allium victorialis var.platyphyllum Extracts on Platelet Aggregation and Vascular Smooth Muscle Cell Proliferation
Kim. Gun-Hee, Jin. Yong-Ri, You. Soon-Hyang, Han. Hyeong-Jun, Lee. Jung-Jin, Yu. Ji-Yeon, Im. Ji-Hyun, Park. Eun-Suk, Kim. Tack-Joong, Ho 한국식품과학회 Food science and biotechnology 4 Pages
한국식품과학회 Food science and biotechnology 2008, Vol.17 No.2 247-250 (4 pages)
