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Microstructural Abnormalities of Basal Ganglia and Thalamus in Bipolar and Unipolar Disorders: A Diffusion Kurtosis and Perfusion Imaging Study
Lianping Zhao, Ying Wang, Yanbin Jia, Shuming Zhong, Yao Sun, Zhifeng Zhou, Zhongping Zhang, Li Huang 대한신경정신의학회 Psychiatry Investigation 12 Pages
대한신경정신의학회 Psychiatry Investigation 2017, 제 14권 제 4호 13 471-482 (12 pages)
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Neuronal Cell Death of Abdominal Ganglia ($A_3$) and Characterization of Neuron - Killing Factor in Ventral Nerve Cord from Sweet Potato Hornworm, Agrius convolvuli
Kim. Mi-Kyung, Lee. Myoung-Hwan, Seo. Dong-Hwan, Choi. Chi-Won, Yun. Chi-Young 한국곤충학회 Korean journal of entomology 8 Pages
한국곤충학회 Korean journal of entomology 2002, Vol.32 No.4 261-268 (8 pages)
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Postembryonic Changes of Locustatachykinin I-Immunoreactive Neurons in Ventral Ganglia of the Common Cutworm, Spodoptera litura
Kang. Hyuno, Kim. Na-Young, Kim. Gee-Sung, Ahn. Ki-Heung, Lee. Bong-Hee 한국곤충학회 Korean journal of entomology 11 Pages
한국곤충학회 Korean journal of entomology 1997, Vol.27 No.3 237-247 (11 pages)
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CT상(上) 확진(確診)된 BASAL GANGLIA INFARCTION의 임상적(臨床的) 관찰(觀察)
이원철, 김영석, 배형섭, 구본홍, Lee. Won-Cheol, Kim. Yeong-Seok, Bae. Hyeong-Seop, Gu. Bon-Hong 대한한방내과학회 대한한방내과학회지 11 Pages
대한한방내과학회 대한한방내과학회지 1986, Vol.3 No.1 11-21 (11 pages)
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Detection of Neuronal Activity by Motion Encoding Gradients: A Snail Ganglia Study
Park. Tae-S., Park. Ji-Ho, Cho. Min-H., Lee. Soo-Y. 대한의용생체공학회 Journal of biomedical engineering research : the official journal of the Korean Society of Medical & 5 Pages
대한의용생체공학회 Journal of biomedical engineering research : the official journal of the Korean Society of Medical & 2007, Vol.28 No.1 24-28 (5 pages)
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Vasogenic Edema of the Basal Ganglia after Intra-Arterial Administration of Nimodipine for Treatment of Vasospasm
Ryu. Chang-Woo, Koh. Jun-Seok, Yu. Seung-Young, Kim. Eui-Jong 대한신경외과학회 Journal of Korean neurosurgical society 4 Pages
대한신경외과학회 Journal of Korean neurosurgical society 2011, Vol.49 No.2 112-115 (4 pages)
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Expression of Deleted in Colorectal Cancer in the Rat Trigeminal Ganglia
Lee. Eun-Joo, Kim. Nam-Ryang, Yoo. Hong-Il, Yang. So-Young, Kang. Jee-Hae, Kim. Hyun-Jin, Kim. Min-Seok, Kim. Sun-Hun 대한구강생물학회 International journal of oral biology : official journal of the Korean Academy of Oral Biology and t 6 Pages
대한구강생물학회 International journal of oral biology : official journal of the Korean Academy of Oral Biology and t 2012, Vol.37 No.4 161-166 (6 pages)
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Effects of foot pressure using the elastic band with rings during sit-to-stand in persons with stroke
Young-In Hwang, Ki-Song Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 4호 1 159-163 (5 pages)
Objective: Persons with stroke have a tendency to exhibit asymmetric weight-bearing during sit-to-stand because due to the attempt to support themselves with the non-paretic foot. However, there are few devices that can assist with sit-to-stand (STS) performance. This study was designed to investigate the use of the elastic band with rings (EBR) in improving weight-bearing effectively in persons with stroke during STS training. Design: Cross-sectional study. Methods: Thirteen stroke survivors... -
Relationship between anticipatory postural adjustment of the trunk, dual tasks and physical performance with chronic stroke survivors
Won Jeong Hwang, Min Kwon Cho, Yi-jung Chung 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 1호 8 44-48 (5 pages)
Objective: The purpose of this study was to investigate the relationship between anticipatory postural adjustment (APA), single task, dual tasks and physical performances. The trunk muscles of APA consist of bilateral erector spinae (ES) and bilateral internal oblique (IO) adnominal muscles, during rapid stepping with the affected or unaffected leg in a sitting posture. Design: Cross-sectional study. Methods: In patients with chronic stroke, electrodes of surface electromyography (EMG) were... -
The effects of motor imagery training on brain waves in persons post-stroke
Hyang-Woon Yoon, Seong-Sik Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 10 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 1호 1 1-10 (10 pages)
Objective: The purpose of this study was to investigate whether motor imagery training (MIT) combined with physical training could have a positive influence on brain waves in stroke patients. Design: Randomized controlled trial. Methods: Twenty-four survivors of a first-time stroke participated in the study. All patients were randomly assigned to one of two groups: (1) MIT group (n=12) and (2) control group (n=12). The MIT group participated in a total of 30 minutes of motor imagery (MI) on each... -
Pressure pain threshold and visual analogue scale changes in the high and low energy extracorporeal shock wave
You-Jin Yang, Seung-Joon Lee, Matthew Choi 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 2호 10 142-147 (6 pages)
Objective: This study aims to investigate high energy and low energy extracorporeal shockwave therapy (ESWT) and which one is more effective for shoulder pain. Design: Single blind randomized controlled trial. Methods: Fifty two subjects with upper trapezius (UT) trigger point (TrP) participated in this study. They were allocated to high energy (n=26) and low energy group (n=26). This study applies ESWT and investigates the changes of pressure pain threshold (PPT) and visual analogue scale... -
Relationships between upper extremity performance and unified Parkinson’s disease rating scale-motor exam
Won-jeong Hwang, Su-jin Hwang, Kyoung-suk Lee, Yi-jung Chung 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 2호 7 99-103 (5 pages)
Objective: Clinical measures that quantify upper extremity function are needed for the accurate evaluation of patients and to plan an intervention strategy. The purpose of this study was to examine the relationship between the Unified Parkinson’s Disease Rating Scale (UPDRS)-Motor Exam and upper extremity performance as a quantifying clinical tool of upper extremity function in persons with Parkinson’s disease. Design: Cross-sectional study. Methods: Thirty-two idiopathic Parkinson’s Disease... -
Multi-voxel magnetic resonance spectroscopy of cerebral metabolites in healthy dogs at 1.5 Tesla
Sooyoung Choi, Yumi Song, Kija Lee, Youngwon Lee, Hojung Choi 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 2호 11 217-224 (8 pages)
This study was conducted to measure the difference in levels of cerebral metabolites in the right and left hemispheres, gray (GM) and white matter (WM), imaging planes, and anatomical regions of healthy dogs to establish normal variations. Eight male Beagle dogs (1 to 4 years of age; mean age, 2 years) with no evidence of neurologic disease were studied. Using the multi-voxel technique on a 1.5 Tesla magnetic resonance imaging scanner, metabolite values (N-acetyl aspartate [NAA], choline [Cho],... -
Immunohistochemical evaluation of the goat forestomach during prenatal development
Angela Garcia, Javier Masot, Antonio Franco, Antonio Gazquez, Eloy Redondo, * 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 4 35-43 (9 pages)
Here we report the detection and distribution of synaptophysin (SPY), non-neuronal enolase (NNE), glial fibrillary acidic protein (GFAP), vimentin (VIM), neuropeptide Y (NPY), and vasoactive intestinal peptide (VIP) expression in the goat forestomach during prenatal development. A total of 140 embryos and fetuses were examined to evaluate protein expression from the first stage of prenatal life until birth. In all cases, SPY immunoreactivity was detected at 53 days gestation in the lamina... -
In vitro and in vivo gene therapy with CMV vector-mediated presumed dog β-nerve growth factor in pyridoxine-induced neuropathy dogs
Jin-Young Chung, Jung-Hoon Choi, Il-Seob Shin, Eun-Wha Choi, Cheol-Yong Hwang, Sang-Koo Lee, Hwa-Young Youn* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 4호 5 367-374 (8 pages)
reaction assessments. Electrophysiological recordings were also normal for the gene therapy group. Histological analysis showed that neither the axons nor the myelin of the dorsal funiculus of L4 were severely damaged in the gene therapy group. In addition, the dorsal root ganglia of L4 and the peripheral nerves (sciatic nerve) did not experience severe degenerative changes in the gene therapy group. This study is the first to show the protective effect of NGF gene therapy in a dog model. -
Immunohistochemical identification and quantitative analysis of cytoplasmic Cu/Zn superoxide dismutase in mouse organogenesis
Jung-Min Yon, In-Jeoung Baek, Se-Ra Lee, Mi-Ra Kim, Beom Jun Lee, Young Won Yun, Sang-Yoon Nam 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 3호 2 233-240 (8 pages)
analysis of SOD1 expression on ED 13.5-18.5 revealed its ubiquitous distribution throughout developing organs. In particular, high levels of SOD1 expression were observed in the ependymal epithelium of the choroid plexus, ganglia, sensory cells of the olfactory and vestibulocochlear epithelia, blood cells and vessels, hepatocytes and hematopoietic cells of the liver, lymph nodes, osteogenic tissues, and skin. Thus, SOD1 is highly expressed at late stages of embryonic development in a cell- and... -
Pyridoxine induced neuropathy by subcutaneous administration in dogs
Jin-Young Chung, Jung-Hoon Choi, Cheol-Yong Hwang, Hwa-Young Youn* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 2호 2 127-132 (6 pages)
days. The dorsal funiculus of L4 was disrupted irregularly in the axons and myelin with vacuolation. The dorsal root ganglia of L4, and sciatic and tibial nerves showed degenerative changes and vacuolation. However, the lateral and ventral funiculi of L4 showed a normal histopathologic pattern. Although this subcutaneous administration method did not cause systemic toxicity and effectively induced sensory neuropathy, this study confirmed the possibility of producing a pyridoxine-induced sensory... -
Enhanced tyrosine hydroxylase expression in PC12 cells co-cultured with feline mesenchymal stem cells
Guang-Zhen Jin, Xi-Jun Yin, Xian-Feng Yu, Su-Jin Cho, Hyo-Sang Lee, Hyo-Jong Lee, Il-Keun Kong* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 4호 10 377-382 (6 pages)
Mesenchymal stem cells (MSCs) secrete a variety of neuroregulatory molecules, such as nerve growth factor, brain-derived neurotrophic factor, and glial cell-derived neurotrophic factor, which upregulate tyrosine hydroxylase (TH) gene expression in PC12 cells. Enhancing TH gene expression is a critical step for treatment of Parkinson's disease (PD). The objective of this study was to assess the effects of co-culturing PC12 cells with MSCs from feline bone marrow on TH protein expression. We... -
Canine model of ischemic stroke with permanent middle cerebral artery occlusion: clinical and histopathological findings
Byeong-Teck Kang, Jong-Hwan Lee, Dong-In Jung, Chul Park, Su-Hyun Gu, Hyo-Won Jeon, Dong-Pyo Jang, Chae-Young Lim, Fu-Shi Quan, 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 4호 9 369-376 (8 pages)
the cerebral cortex and basal ganglia. These lesions were well-defined and sharply demarcated from adjacent brain parenchyma with a homogenous appearance. No abnormalities of the cerebrospinal fluid were observed. At necropsy, atrophic and necrotic lesions were observed in the cerebral cortex. The cerebral cortex, basal ganglia, and thalamus were partially unstained with triphenyl-tetrazolium chloride. Histopathologically, typical features of infarction were identified in cortical and thalamic... -
Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen
Yoot Mo Lee, Min Jae Seong, Jae Woong Lee, Yong Kyung Lee, Tae Myoung Kim, Sang-Yoon Nam, Dae Joong Kim, Young Won Yun, Tae Seon 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 5 27-38 (12 pages)
Bisphenol A (BPA), a ubiquitous environmental contaminant, has been shown to cause developmental toxicity and carcinogenic effects. BPA may have physiological activity through estrogen receptor (ER) -α and -β, which are expressed in the central nervous system. We previously found that exposure of BPA to immature mice resulted in behavioral alternation, suggesting that overexposure of BPA could be neurotoxic. In this study, we further investigated the molecular neurotoxic mechanisms of BPA. BPA... -
Site adaptations of Acanthogyrus (Acanthosentis) tilapiae: Observations through light and scanning electron microscopy
Mahmoud E. Bayoumy, Osman K. Abd El-Hady, Hussein A.M. Osman 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 6 339-342 (4 pages)
towards the posterior of the body. The first row is supported by unmodified hooks. The parasite tegument has a series of alternative folds and a large number of pores. Sensory ganglia are located on the surface of the proboscis and body. Acanthogyrus (Acanthosentis) tilapiae provokes an aggressive host response indicated by hyperplasia of the intestinal goblet cells and focal eosinophil infiltrations. This acanthocephalan parasite shows a highly modified adaptation to its site of host infection. -
Immunohistochemical localization of calcium binding proteins and some neurotransmitters in myenteric plexus of goat stomach
Heungshik S. Lee, Young Sam Nam 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 2 315-319 (5 pages)
To understand the neurochemical properties of the gastric myenteric plexus of ruminants, the expression patterns of calbindin D-28k (CB), calretinin (CR), substance P (SP) and calcitonin gene-related peptide (CGRP) were explored in the Korean native goat. In gastric myenteric plexus, CB and SP immunoreactivity were observed in round- or ovalshaped neurons. CR and CGRP immunoreactivity were detected only in the nerve fibers. This immunohistochemical localization of CB, CR, CGRP and SP in the... -
Immunohistochemistry of Voltage-Gated Calcium Channel α1B Subunit in Mouse Cerebellum
Seung-Hyuk Chung, Kyung-Youl Lee, Ki-Hyung Kim, Chul-Tae Kim, Nam-Seob Lee, Kazuhiko Sawada, Hiromi Haga, Byung-Chul Lee, Yoshih 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 3호 5 175-178 (4 pages)
Secretion of neurotransmitters is initiated by voltage-gated calcium influx through presynaptic, voltage- gated N-type calcium channels. However, little is known about their cellular distribution in the mouse cerebellum. In the cerebellum, alpha1B immunoreactivity is found mainly on the cell bodies of all Purkinje cells. In addition, the immunoreactivity was detected on a subset of Purkinje cell dendrites, clustered to form a parasagittal array of bands. In the anterior lobe vermis,... -
Assessment of Replication and Virulence of Attenuated Pseudorabies Virus in Swine
T. J. Newby, D. P. Carter, K.-J. Yoon, M. W. Jackwood and P. A. Hawkins 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 2호 1 61-66 (6 pages)
A nonclinical study was conducted to characterize the replication behavior of a modified live gE-deleted pseudorabies virus (PRV MS) in swine and potential for reversion to virulence after animal passages. Two to 3 week-old weaned pigs, negative for PRV, were maintained in isolation and challenged by intranasal instillation. For the first passage, 6 pigs were given 1 mL of PRV MS (10(7.3)TCID(50)/mL) and 2 were necropsied at 3, 4 and 5 days post-inoculation (PI). Brain and secondary lymphoid... -
발생중인 병아리의 사이뇌에서 NPY 양성반응세포의 분포
이미영, 박일권, 이경열, 권효정, 송치원, 박미선, 이강이 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 14 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2002, 제 42권 제 1호 2 7-20 (14 pages)
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관악기 연주 후 악기에 잔존하는 구강 상피 잔사, 음식물 입자와 타액은 미생물 서식에 좋은 환경을 제공한다. 이에 관악기의 위생 관리에 소홀할 경우 악기를 매개로 한 병원성 미생물의 전염에 대한 우려가 있다. 하지만 국내에 악기에 존재하는 감염균과 악기 위생 관리에 대한 연구, 조사는 극히 부족한 실정이다. 본 연구는 국제 연구 문헌 검색을 통해 실험과 임상 진단이 이루어진 연구를 선별하였으며 이들 분석을 통해 관악기에서 확인되는 미생물을 열람하고 이와 관련하여 발생할 수 있는 질환에 대해서 고찰하였다. 취주...
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디지털 콘텐츠 중독과 관련된 두뇌 영역 : 인터넷과 비디오 게임 중독자의 뇌영상을 중심으로
권승혁, 엄증태, 권용주 한국교원대학교 뇌기반교육연구소 Brain & Learning 10 Pages
한국교원대학교 뇌기반교육연구소 Brain & Learning 2014, 제 4권 제 1호 2 11-20 (10 pages)
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Golgi and Cajal’s scientific inquiry processes on the Neuron
Won Jung Kim, Yong-Ju Kwon 한국교원대학교 뇌기반교육연구소 Brain & Learning 16 Pages
한국교원대학교 뇌기반교육연구소 Brain & Learning 2012, 제 2권 제 1호 2 12-27 (16 pages)
생물학사를 적용한 생물 탐구는 과학자들의 연구 과정을 고찰하고 학생들이 과학자의 탐구 과정을 이해할 수 있는 효과적인 방법이다. 본 연구는 1906년 노벨 생리의학상 공동 수상자인 골지와 카잘의 연구 과정을 되짚어본다. 이 연구의 목적은 먼저 골지와 카잘의 연구 과정을 살펴보고, 이를 바탕으로 뉴런과 관련한 내용을 학습할 때 활용할 수 있는 생물학사 기반 탐구 활동지를 개발하는 것이다. 이를 위해 먼저 과학 탐구 과정에 대해 소개하였다. 이 과정에 각각의 과학자가 수행한 탐구 과정을 대응시키는 과학자의 탐구 과정... -
Tricyclic antidepressant amitriptyline inhibits 5-hydroxytryptamine 3 receptor currents in NCB-20 cells
Yong Soo Park, Seok Ho Myeong, In-Beom Kim, Ki-Wug Sung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 12 585-595 (11 pages)
Amitriptyline, a tricyclic antidepressant, is commonly used to treat depression and neuropathic pain, but its mechanism is still unclear. We tested the effect of amitriptyline on 5-hydroxytryptamine 3 (5-HT3) receptor currents and studied its blocking mechanism because the clinical applications of amitriptyline overlapped with 5-HT3 receptor therapeutic potentials. Using a whole-cell voltage clamp method, we recorded the currents of the 5-HT3 receptor when 5-HT was applied alone or co-applied... -
Antipruritic effect of curcumin on histamine-induced itching in mice
Han Kyu Lee, Seok Bum Park, Su-youne Chang, Sung Jun Jung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 8 547-554 (8 pages)
Itching is a common clinical symptom of skin disease that significantly affects a patient’s quality of life. Transient receptor potential vanilloid 1 (TRPV1) receptors of keratinocytes and peripheral nerve fibers in skin are involved in the regulation of itching as well as pain. In this study, we investigated whether curcumin, which acts on TRPV1 receptors, affects histamine-induced itching in mice, using behavioral tests and electrophysiological approaches. We found that histamine-induced... -
Effects of acidic pH on voltage-gated ion channels in rat trigeminal mesencephalic nucleus neurons
Jin-EonHan, Jin-HwaCho, In-SunChoi, Do-YeonKim, Il-SungJang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.2 9 215-223 (9 pages)
The effects of acidic pH on several voltage-dependent ion channels, such as voltage-dependent K+ and Ca2+ channels, and hyperpolarization-gated and cyclic nucleotide-activated cation (HCN) channels, were examined using a whole-cell patch clamp technique on mechanically isolated rat mesencephalic trigeminal nucleus neurons. The application of a pH 6.5 solution had no effect on the peak amplitude of voltage-dependent K+ currents. A pH 6.0 solution slightly, but significantly inhibited the peak... -
Inducibility of human atrial fibrillation in an in silico model reflecting local acetylcholine distribution and concentration
MinkiHwang, Hyun-SeungLee, Hui-NamPak, EunBoShim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 14 111-117 (7 pages)
Vagal nerve activity has been known to play a crucial role in the induction and maintenance of atrial fibrillation (AF). However, it is unclear how the distribution and concentration of local acetylcholine (ACh) promotes AF. In this study, we investigated the effect of the spatial distribution and concentration of ACh on fibrillation patterns in an in silico human atrial model. A human atrial action potential model with an ACh-dependent K+ current (IKAch) was used to examine the effect of vagal... -
The Inhibitory Mechanism of Gentamicin on Electrical Field Stimulation Response in Rat Bladder Smooth Muscle
ChangHoMin, YiYiWang, JinhyungBae, JungHoonHan, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.5 11 473-478 (6 pages)
To see the inhibitory mechanism of gentamicin in response to electrical field stimulation (EFS) using the rat bladder smooth muscle, atropine or guanethidine was treated but had no effect. Methylsergide, a non-selective 5-HT1, 5-HT2 receptor antagonist was also treated but had on effect. Kinase inhibitors, such as chelerythrine (PKC inhibitor), ML-9 (MLCK inhibitor), or Y27632 (rho kinase inhibitor) were pretreated before gentamicin treatment, but did not have effect. For U73122, a phospholipase...


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