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Correlation between mEPSC Amplitude and Rise Time upon the Blockade of AMPA Receptor Desensitization at Hippocampal Synapses
SuHyunJung, SukwooChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.2 3 81-86 (6 pages)
Conventional views of synaptic transmission generally overlook the possibility of "postfusional- control" the regulation of the speed or completeness of transmitter release upon vesicular fusion. However, such regulation often occurs in non-neuronal cells where the dynamics of fusion-pore opening is critical for the speed of transmitter release. In case of synapses, the slower the transmitter release, the smaller the size and rate-of-rise of postsynaptic responses would be expected if... -
Effect of Stimulus Rate and Gender on Auditory Brainstem Response in Korean Young Adults
Chul-Hee Choi, Ki-Hyeon Jang, Seong Hee Choi 한국청각언어재활학회 Audiology and Speech Research 16 Pages
한국청각언어재활학회 Audiology and Speech Research 2015, 제 11권 제 2호 5 140-155 (16 pages)
The main objective of this study was to determine the effect of stimulus rate and gender on auditory brainstem response (ABR) latency and amplitude in Korean young adults. A total of thirty young adults consisting of fifteen males and fifteen females participated in the study. We performed this study by analyzing the latencies and amplitudes of ABR wave I, Ⅲ, and V as a function of low stimulus rate and gender. The stimulus repetition rate was changed in five steps: 8, 16, 21, 32, and 64/s.... -
Electroretinography recordings using a light emitting diode active corneal electrode in healthy beagle dogs
Yoshiki Itoh, Seiya Maehara, Norihiko Itoh*, Kazuto Yamashita, Yasuharu Izumisawa 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 1호 11 77-84 (8 pages)
in b-wave amplitude along with b/a ratio of the combined rod-cone response were found between the young and adult animals as well as young and senile dogs. No significant differences were observed between the left and right eyes. ERG variables in beagle dogs differed by age due to age-related retinal changes. Thus, we propose that normal ERG ranges should be determined according to age in each clinic and laboratory using its own equipment because each institution usually has different systems or... -
Potassium Currents in Isolated Deiters' Cells of Guinea Pig
JongWooChung, EuiCholNam, WonTaeKim, JaeBoumYoum, ChaeHunLeem 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.6 10 537-546 (10 pages)
Deiters' cells are the supporting cells in organ of Corti and are suggested to play an important role in biochemical and mechanical modulation of outer hair cells. We successfully isolated functionally different K+ currents from Deiters’ cells of guinea pig using whole cell patch clamp technique. With high K+ pipette solution, depolarizing step pulses activated strongly outward rectifying currents which were dose-dependently blocked by clofilium, a class III anti-arrhythmic K+ channel blocker.... -
Gap Junction Contributions to the Goldfish Electroretinogram at the Photopic Illumination Level
Doh-YeonKim, Chang-SubJung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.3 11 219-224 (6 pages)
Understanding how the b-wave of the electroretinogram (ERG) is generated by full-field light stimulation is still a challenge in visual neuroscience. To understand more about the origin of the b-wave, we studied the contributions of gap junctions to the ERG b-wave. Many types of retinal neurons are connected to similar and different neighboring neurons through gap junctions. The photopic (cone-dominated) ERG, stimulated by a small light beam, was recorded from goldfish (Carassius auratus) using... -
(? )-Epigallocatechin Gallate Inhibits the Pacemaker Activity of Interstitial Cells of Cajal of Mouse Small Intestine
KweonYoungKim, SooJinChoi, HyukJinJang, DongChuanZuo, PawanKumarShahi, ShankarPrasadParajuli, CheolHoYeum, PyungJinYoon, SeokChoi, JaeYeo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.3 4 111-116 (6 pages)
in a dose-dependent decrease in the frequency and amplitude of pacemaker currents. SQ-22536, an adenylate cyclase inhibitor, and ODQ, a guanylate cyclase inhibitor, did not inhibit the effects of EGCG. EGCG-induced effects on pacemaker currents were not inhibited by glibenclamide, an ATP-sensitive K＋ channel blocker and TEA, a Ca2＋-activated K＋ channel blocker. Also, we found that EGCG inhibited the spontaneous [Ca2＋]i oscillations in cultured ICC. In conclusion, EGCG inhibited the pacemaker... -
Effects of Phenylephrine on the Excitability of Medial Vestibular Nuclear Neurons in Rats
Han-SeongJeong, HaeRyongHuh, Myung-JooJang, Seol-HeeHong, SujeongJang, JinPark, Seung-HanLee, Jae-HaKim, Jong-SeongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.3 3 131-136 (6 pages)
enzymatic digestion, dissociated medial vestibular neurons were transferred to a recording chamber mounted on an inverted microscope, and spontaneous action potentials were recorded by standard patch-clamp techniques. In current-clamp mode, the frequency of spontaneous action potential of medial vestibular nuclear neurons was decreased by phenylephrine (n=15). Phenylephrine increased the amplitude of afterhyperpolarization without changes in the resting membrane potential and spike width. In... -
Inhibitory and Excitatory Postsynaptic Currents of Medial Vestibular Nucleus Neurons of Rats
SangWooChun, JeongHeeChoi, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 2 59-63 (5 pages)
low frequency (1.5⁑0.4 Hz), small amplitude (13.9⁑1.9 pA), and rapid decay kinetics (2.8⁑0.2 ms). The majority (15/21) displayed linear I-V relationships, suggesting the presence of GluR2-containing AMPA receptors. Only 35% of recorded MVN neurons showed NMDA mediated currents, which were characterized by small amplitude and low frequency. These results suggest that the MVN neurons receive excitatory inputs mediated by AMPA, but not kainate, and NMDA receptors, and inhibitory... -
Effects of Noradrenaline on the Membrane Potential of Prostatic Neuroendocrine Cells of Rat
JunHeeKim, SunYoungShin, Dae-YongUhm, SungJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.1 9 47-52 (6 pages)
The prostate gland contains numerous neuroendocrine cells that are believed to influence the function of the prostate gland. Our recent study demonstrated the expression of both α1- and α2-ARs, signaling the release of stored Ca2 and the inhibition of N-type Ca2 channels, respectively, in rat prostate neuroendocrine cells (RPNECs). In this study, the effects of NA on the resting membrane potential (RMP) of RPNECs were investigated using a whole-cell patch clamp method. Fresh... -
Electroencephalographic Correlation Dimension Changes with Depth of Halothane
MaanGeeLee, EunJuPark, JungMeeChoi, MoonHanYoon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.5 5 491-499 (9 pages)
the last 5-mins of EEG recording at each concentration level. Correlation coefficients between the parameters and the movements were calculated. Standardized values of three parameters, betaL power, median power frequency (MPF), and D2 were derived by calculation based on the number of animals showing the movement in response to a tail clamp. The betaL power had the largest correlation coefficient to spontaneous movement and to the response to a tail clamp than any other band parameter. MPF had... -
Comparative Effects on Secretion of LH, FSH, Prolactin, and Testosterone by Chronic and Direct Hypothalamic Administration of Nonylphenol to Adult Male Rats
Kun-SukPark, Won-CheoulJang, Mee-KyungKim, Hyung-GunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 12 215-222 (8 pages)
Nonylphenol (NP) is a widespread environmental pollutant that has been shown to exert both toxic and estrogenic effects on mammalian cells. As the effects of NP on the reproductive system of adult male vertebrates are virtually unknown, we investigated not only the changes of reproductive hormone secretion in serum after chronic exposure to NP but also, in order to identify the site of its action, the reproductive hormone secretion in serum 48 hours after microinfusion of NP within hypothalamic... -
Neuroendocrine Control of Gonadotropin Secretion during the Menstrual Cycle
Ryu Kyung-Za 대한약리학회 대한약리학잡지 20 Pages
대한약리학회 대한약리학잡지 1987, 제 23권 제 2호 1 57-76 (20 pages)
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백서의 뇌내 Opiate 수용체의 일중 변동에 미치는 Phenobarbital의 영향
박영걸(Yeoung-Gul Park), 김기원(Kee-Won Kim), 조규박(Kyu-Park Cho) 대한약리학회 대한약리학잡지 14 Pages
대한약리학회 대한약리학잡지 1985, 제 21권 제 2호 6 128-141 (14 pages)
실험적으로 명암에 적응시킨 백서의 뇌내 specific opiate binding과 β-endorphin 함량 일중변동에 미치는 지속적인 암적응, phenobarbital 장기처리의 영향을 관찰하고 opiate recptor binding과 β-endorphin 함량 양자간의 관계를 추구하여 다음과 같은 성적을 얻었다. 1. L : D, 12 : 12 주기에 적응시킨 대조군에서 maximum (3H)-morphine binding과 뇌내 β-endorphin 함량은 각각 22시 및 06시에 최고에 달하는 매우 특이한 일중변동을 보였고 24시간 평균 (3H)-morphine binding 및 뇌내 β-endorphin 함량은 각각 0.45+0.03... -
Mismatch Negativity(MMN) 반응을 이용한 주의집중 정량화에 관한 연구
하은정, 임덕환 한국청각언어재활학회 Audiology and Speech Research 6 Pages
한국청각언어재활학회 Audiology and Speech Research 2006, 제 2권 제 2호 7 135-140 (6 pages)
MMN 검사는 대상자의 주의집중 없이도 검사가 가능하여 유아나 검사하기 어려운 환자 집단에 대한 임상적인 중요성을 가지고 있다. 이로 인해 주의력 결핍 장애, 청각 장애 아동, 실어증, 정신분열증 환자, 신생아 등의 음 지각 처리 능력 측정이 가능한 것으로 보고되고 있다.6) 이러한 집 단의 사람들은 특히 주의집중 능력 자체가 평상 시 생활 하거나 재활을 받을 때 영향을 미치는 요소가 될 수 있다. 그러나 현재에는 이러한 주의집중에 대한 정도를 측정할 수있는 객관적 평가 도구가 부족한 실정이다. 청각장애 아동과 정상... -
Preparation and application of reduced graphene oxide as the conductive material for capacitive deionization
Ayu Tyas Utami Nugrahenny, Jiyoung Kim, Sang-Kyung Kim, Dong-Hyun Peck, Seong-Ho Yoon, Doo-Hwan Jung 한국탄소학회 Carbon Letters 7 Pages
한국탄소학회 Carbon Letters 2014, Vol.15 No.1 5 38-44 (7 pages)
This paper reports the effect of adding reduced graphene oxide (RGO) as a conductive material to the composition of an electrode for capacitive deionization (CDI), a process to remove salt from water using ionic adsorption and desorption driven by external applied voltage. RGO can be synthesized in an inexpensive way by the reduction and exfoliation of GO, and removing the oxygen-containing groups and recovering a conjugated structure. GO powder can be obtained from the modification of Hummers...
