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Production of α 1,3-galactosyltransferase targeted pigs using transcription activator-like effector nuclease-mediated genome editing technology
Jung-Taek Kang, Dae-Kee Kwon, A-Rum Park, Eun-Jin Lee, Yun-Jin Yun, Dal-Young Ji, Kiho Lee, Kwang-Wook Park 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 1호 11 89-96 (8 pages)
Recent developments in genome editing technology using meganucleases demonstrate an efficient method of producing gene edited pigs. In this study, we examined the effectiveness of the transcription activator-like effector nuclease (TALEN) system in generating specific mutations on the pig genome. Specific TALEN was designed to induce a double-strand break on exon 9 of the porcine α1,3-galactosyltransferase (GGTA1) gene as it is the main cause of hyperacute rejection after xenotransplantation.... -
Minimal systems analysis of mitochondria-dependent apoptosis induced by cisplatin
Ji-YoungHong, KenjirouHara, Jun-WooKim, EisukeF.Sato, EunBoShim, Kwang-HyunCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.4 6 367-378 (12 pages)
Recently, it was reported that the role of mitochondria-reactive oxygen species (ROS) generating pathway in cisplatin-induced apoptosis is remarkable. Since a variety of molecules are involved in the pathway, a comprehensive approach to delineate the biological interactions of the molecules is required. However, quantitative modeling of the mitochondria-ROS generating pathway based on experiment and systemic analysis using the model have not been attempted so far. Thus, we conducted experiments... -
Impact of single metal oxide and coal ash on secondary ultrafine particle generation through SO2 and NO2 heterogeneous reaction
Ru-Jiao Song, Zi-Xiang Xu, Joo-Chang Park, Li-Hua Xu, Hyung-Taek Kim 한국열환경공학회 열환경공학 19 Pages
한국열환경공학회 열환경공학 2020, 제 15권 1호 4 28-46 (19 pages)
Particulate matter research is of great significance in solving atmospheric environment problems. The heterogeneous reaction of mixed gas on different mineral oxides and coal ash was studied based on a laboratory-built aerosol generating reactor. The product formed on particles was investigated by ion chromatography (IC). SO2 and NO2 could react on oxides to form secondary particles and the order of reactivity of mineral oxides under laboratory reaction conditions is: Al2O3>MgO>CaO>>SiO2, Fe2O3.... -
Influence of hot-pressing pressure on the densification of short-carbon-fiber-reinforced, randomly oriented carbon/carbon composite
Thakur Sudesh Kumar Raunija and Sharad Chandra Sharma 한국탄소학회 Carbon Letters 9 Pages
한국탄소학회 Carbon Letters 2015, Vol.16 No.1 4 25-33 (9 pages)
The prime objective of this research was to study the influence of hot-pressing pressure and matrix-to-reinforcement ratio on the densification of short-carbon-fiber-reinforced, randomly oriented carbon/carbon-composite. Secondary objectives included determination of the physical and mechanical properties of the resulting composite. The ‘hybrid carbon-fiberreinforced mesophase-pitch-derived carbon-matrix’ composite was fabricated by hot pressing. During hot pressing, pressure was varied from 5... -
ON FARTHEST POINTS IN METRIC SPACES
Narang. T.D. NARANG 한국수학교육학회 Journal of the Korea Society of Mathematical Education. 한국수학교육학회지. Series B, Pure and applied mathem 7 Pages
한국수학교육학회 Journal of the Korea Society of Mathematical Education. 한국수학교육학회지. Series B, Pure and applied mathem 2002, Vol.9 No.1 1-7 (7 pages)
