Thermal neutron activation analysis was applied to determine the trace amount of Vanadium and Manganese in Buyo and Kumsan Ginseng. These elements have been regarded to have great nutritional value and one of the indispensable factor in the growth of ginseng. The TRIGA MARK II Reactor in Atomic Energy Research Institute was used for the neutron source. The samples were irradiated for 10 minutes for Vanadium and for 5 minutes for Manganese at the neutron flux of about $1.28{ imes}10^{12}n/cm^2/sec$ and the RCL 256 Channel Pulse-Height Analyzer connected with $2"{ imes}2"$ Nal(Tl) was used for activity determination. The amounts were about 0.02 ppm for Vanadium and 20 ppm for Manganese, and it was also found that the amounts of the elements were slightly different depending on the kinds of ginsengs.