The diagnostic roentgenologic osseous changes in congenital syphilis have been most definitely defined by McLean in 1931. The high indicence of skeletal involvement in young syphilitic infants gas been provedbeyond question and the roentgenographic features of these lesions are well known. The material gere reviewed consisted of 5 infants of congenital syphilis under one year age. Stated briefly, the signs readly recognized and of chief diagnostic importance are; 1. Well defined saw-tooth metaphysis. 2. Single thickened transverse lines of increased density at the ends of shafts. 3. Transverse zone of diminished density in the ends of shafts plus prallel thickened transverse increased density. 4. Radiolucent density occupying the ends of the shafts. 5. Bilateral symmetical osteomyelitis of proximal medial aspects of the long bone. 6. Localized periosteal clocking occuring in the shafts of long bone.