Selective renal arteriography has been recognized as highly diagnostic and widely popularized method for detection and evaluation of various renal diaseases, especially of malignant tumors. Since Abrams had advocated epinephrine pharmacoangiography, a few reports on this subject has appeared in the literature. At Department of Radiology, Seoul National University Hospital, a total 22 patients whom renal disease was suspected, were studied with selective renal arteriography, during from August 1971 to March 1973. Aortogram, selective renal arteriogram and epinephrine pharmacoangiogram were comprehensively analized. In all of 7 cases which are angiographically normal, proper contraction of renal artery to epinephrine is observed. In 3 cases of simple cyst and 3 cases of other benign process, again proper response to epinephrine is noted. In all 8 cases of proven renal cell carcinoma and a case of transitional carcinoma, there is abnormal response to epinephrine, i.e. lack of con raction, however. It appears to be clear that epinephrine pharmacoangiography is safe and excellent modality for early and accurate diagnosis of malignant renal tumors.