Experiments were conducted with rabbits to study the possibility that blood flow of submaxillary glands may play a role in salivary secretion. Varoious dosage of propranolol and isoproterenol were given via the jugular vein and tha investigation of blood flow in submaxillary glands were performed by means of rheographic method. Conclusion were that propranolol was affected scarecely and isoproterenol were affecred dramatically of blood flow in sibmaxillary gland.