흰 쥐의 간 homogenate에 alloxan을 가하고 succinic dehydrogenase-cytochrome oxidase 계열과 ascorbic acid 산화에서 alloxan의 작용을 관찰한 바 다음과 같은 결론을 얻었다. 1. Alloxan에 의한 ascorbic acid 산화에 관한 효소는 alloxan을 첨가하였을때에 불안정하여 쉽게 파괴되고 $38^{circ}C$ 에서는 alloxan 첨가후 10분에서 거의 완전히 그 기능을 상실하였다. 그리고 이 효소는 cytochrome c 와는 아무 관계가 없었다. 2. Alloxan은 succinic dehydrogenase 활성을 약간 억제하나 의의있는 정도는 아니었다.
Alloxan was added in rat liver homogenate and the effect of alloxan on the succinic dehydrogenase-cytochrome oxidase system and on oxidation of ascorbic acid was observed and the following results were obtained. 1) The alloxan dependent ascorbic acid oxidation enzyme was unstable and easily destroyed with the addition of alloxan. The enzyme has lost almost all its function in 10 minutes at $38^{circ}C$ after addition of alloxan and the enzyme has no relationship with cytochrome c. 2) Alloxan inhibited activity of succinic dehydrogenase insignificantly.
