Fifty six patients with medulloblastoma who has been treated at the University of Minnesota since 1942 were retrospectively evaluated. Patients who received irradiation to the entire central nerve system has better survival rates than those receiving limited irradiation. A control rate of 70% had been obtained in 15 patients who treated with 5000 rads/7-8week to the whole brain and 3600 rads to the spinal cord. There was a 50% incidence of cauda equina syndrome in 14 patients who received supplemental intrathecal Au-198. Reirradiation of intracranial gives good symptomatic palliation and may occasinally yield a long-term survivors.