The mandibular canal must be considered carefully during the surgical treatment, especially surgical extraction of the impacted tooth and intraosseous implant, because it contains the important inferior alveolar nerve and vessels. The author investigated the curvature of the mandibular canal and its relation to the mandibular molars and positional realtion between the mental foramen and the mandibular premelors in orthopantomogram. The materials consisted of 441 orthopantomograms divided four groups; Group Ⅰ consisted of 56 males and 44 females from 1 to 6 years of age, Group Ⅱ consisted of 58 males and 45 females from 7 to 12 years of age, Group Ⅲ consisted of 65 males and 33 females from 13 to 18 years of age, Group Ⅳ consisted of 86 males and 54 females over 19 years of age. The results were as followings; 1. The curvature of mandibular canal was 144.50° in Group Ⅰ, 144. 29° in Group Ⅱ, 148.11° in Group Ⅲ, 147.33° in Group Ⅳ. 2. The curvature of mandibular canal was located most frequently on the area between mandibular 1st molar and mandibular 2nd molar in Group Ⅰ (42%) and on the mandibular 2nd molar area in Group Ⅱ (54%), Group Ⅲ (59%), Group Ⅳ (53%). 3. The position of mental foramen was most frequently below the mandibular 1st premolar in Group Ⅰ (58%), between the mandibular 1st premolar and the 2nd premolar in Group Ⅱ (62%), Group Ⅲ (47%), and below the mandibular 2nd premolar in Group Ⅳ (58%).