An Application of Experimental Designs to Improve the quality of Industrial product : optimization Methodology of statistical model. The primary object of this paper is to aid scientists and Engineers, in applying response surface procedures to obtain operating conditions for many technical fields, particularly for industrial manufacturing processes. The problem considered in this paper is to select technically and scientifically some important factors affecting the quality of products through the experimental design and analysis of response surface. Even though the mathematical model is unknown these statistical analysis can be applicable to control the quality of industrial products and to determine optimum operating conditions for many technical fields, particularly, for industrial manufacturing processes. This paper proposes a method to obtain the optimum operating condition, and how to find the condition by using table of orthogonal array experiments, and optimization methodology of statistical model.