Malignant fibrous histiocytoma is a rare malignant tumor of histiocytic origin, arising from either bone, or soft tissue. Six cases of malignant fibrous histiocytoma are presented with emphasis on radiographic features. Five cases are of primary bone origin and one of soft tissue. Ill-defined osteolytic bone destruction with no sclerosis and with no periosteal reaction is the principal radiologic feature of the malignant fibrous histiocytoma of bone. Therefore, malignant fibrous histiocytoma should be considered in differential diagnosis of primary intraosseous or extraosseous malignancies.