The study was undertaken to evaluate the normal microangiographic findings of the brain and to assess the effect of varying perfusion technique of the microangiography in the rat. All the icrovascular structures including fine medullary branches of the perforating arteries and anastomotic capillary networks are well visualized in both 15 minutes-perfusion group and 30 minutes-perfusion group. But many of the microangiographic findings between these groups. There is poor perfusion of the microvascular structures in the 3rd group, the group with perfusion for 30 minutes without lilgation of aorta below the needle insertion site. The new, simple perfusion technique should be developed to obtain the best quality of the microan- giographic findings in the brain of the experimental animals.