This study was attempted to investigate the main factors affecting health perception of the patients following cardiac valve replacement surgery. Data were collected from Sept. 1 to Oct. 31, 1984 through administration of questionnaire developed for this study by the researcher. The subject was 95 patients who received follow up care following cardiac valve replacemert surgery at S.N.U.H. The data were analyzed by T-test, oneway ANOVA, pearson correlation and multiple regression according to dependent variables. The results were as follows. circled1 Average self-health perception of those patients. were 4.62, (maximum; 7 minimum; 1) and they showed on affirmative response for their health condition, circled2 There was significant difference in health perception according to sex difference. Men had higher health perception than women. (t=2,83, p=0.006) circled3 There was significant difference in health perception according to occupation. Those who had occupation showed higher health perception those who had no occupation. (t=3.25, p=0.002) circled4 The longer post-operative period elapsed, the higher health perception was, and there was significant difference in health perception (f=0.2958, p=0.002). circled5 The higher age was, the lower health perception was, and there was a significant difference in health perception. (${gamma}$= -0.2485, p=0.008) circled6 The fewer subjective psychosomatic symptoms were, the higher health perception was, and there was a significant difference in health perception. (f = -0.4988, p=0.0000) circled7 The more active daily activities were, the higher health perception was, and there was a significant difference in health perception. (${gamma}$=0.6359 p=0.0000) circled8 The main factors predicting health perception .are like these. circled1 Daily activities (42.7%), highest variable. circled2 Psychosomatic symptoms (7.29%) circled3 Elapsed period after cardiac valve replacement surgery (1.89%) circled4 Existence of occupation (1.87%) circled5 Sex (1.78%) circled6 Age (0.8%).