Before the advent of CT, disease processes of the mesentery were dentified indirectly by displacement of opacified bowel. Although ultrasound has proved to be useful in imaging mesenteric lesion, it has many limitations in detection pathologic change of adjacent mesentery, relationship between mesenteric lesions and surrounding organs, but CT withits excellent depction of cross-sectional anatomy gines good definition of mesentery and diseases affecting mesentery. Authors analyzed CT features of pathologically or surgically proven mesenteric diseases for recent 2 years at Keimyung Univ. Dongsan Mdeical Center. RESULTS : 1. Of 42 cases, 234 were male and 19 were female, and age ranged from 4 to 74 years old, most common in 7 the decade. 2. The most common mesenteric mass was lynphoma, followed by primary mesenteric turors, abscess, tuberculosis, metastasis and hematoma. 3. Mesenteric cysts were well defined, thin walled cystic mass with trequent internal septations. 4. In all ca es of peritoneal mesothelioma, there were linear or granular infiltration on emsentery and omentum, accompanied by ascites. 5. Mesenteric fibroma was round soft tissue mass of homogeneous attenuation, 6. Of 14 cases of lymphoma, 12 cases showed variable pattern of mesenteric mass: round, cake-like, ill-defined mass and mixed pattern. 7. Mesenteric abscess revealed round cystic mass with irregular wall in 4 cases, and irregular linear infiltratinos and adjacent in all. 8. Mesenteric hematomas were cake-like mass in 1 case, and ill-defined triangular mass in two. 9. Three of 4 cases of metastatic mesenteric masses have large solid round masses, but one case shows shellate pattern of mesentery. 10. Abdominal tuberculosis were ill-defined mass in 2 cases, and stellate pattern in two. 11. CT was excellent modality in detection of mesenteric lesion, and also useful in differential diagnosis of mesenteric disease by analysis of shape, size, extent, attenuation value, contrast enhancement pa tern of the lesion and adjacent mesenteric change