Personal computer based measurement and control system was constructed and tested in order to fiexibly apply it to laboratoy experiments in which environmental factors such as temperature, humidity, pH, DO and gases should be measured and controlled. Personal computer FC-80 was successively interfaced to the input-output system made up of PPI, A/D converter, D/A converter, programmable timer and USART boards. To test the system, pH control experiment was executed and the pH of the solution could be measured, expressed on the monitor and controlled at constant value.