진주담치의 homogenate로부터 음이온교환수지와 친화력 크로마토그라피를 이용하여 렉틴성분을 분리정제하였다. 이 렉틴성분은 전기영동상에서 주변 하나의 띠로 나타났으며 분자량은 약 18,000 dalton이었고 monomer로 생각된다. 이 렉틴은 토끼 적혈구를 강하게 응집시켰으며 사람혈액형에 대하여는 특이성이 낮았고 그중에서 A형 적혈구를 잘 응집시켰다. 이 렉틴의 적혈구응집활성은 galactose 및 galactose의 유도체에 의해 저해되었으며 EDTA, $Hg^{++}$및 $Mg^{++}$ 등의 양이온에 의해서도 저해되었다. 이 렉틴은 당을 함유하지 않은 단백질로 나타났으며 열에 불안정하였다.
A lectin from the mussel, Mytilus edulis, was isolated and purified by using DEAE-cellulose and affinity chromatography on N-acetyl-D-galactosamine-Agarose. The purification acheived was 6,628 fold from 20,000 g homogenate with a yield of 58.1%. Its isoelectric point was around pH 7.8 and its molecular weight was estimated to be about 18,000 daltons by Sephadex G-75 gel filtration and SDS-polyacrylamide gel electrophoresis. The mussel lectin was stable below $35^{circ}C$. The lectin agglutinated rabbit erythrocytes strongly and showed the broad specificity to human blood groups. The hemagglutinating activity of the lectin was inhibited by sugars; galactose and its derivatives, and cations; EDTA, $Hg^{++}$, and $Mg^{++}$. This lectin seemed to have no carbohydrates.
