The effect of yohimbine HCI(0.25mg / kg) on xylazine(0.15mg /kg) induced depression of rumen motility was investigated by means of electromyography of luminal wall in korean native goats. Yohimbine was administrated 5 min pre-xylazine injection, 5 min and 15 min after xylazine injection. The duration of lumen motility in cases of xylazine alone administration, yohimbine administration 5 min pre-xylazine injection, 5 min post-xylazine, and 15 min post-xylazine was 47-64, 36-40, 28-29, and 15-17 min, respectively. It is demonstrated that lumen contractions were inhibited by xylazine and the inhibition was most rapidly reversed by the administration of yohimbine 15 min after xylazine injection in which goat was completely sedated.