Early diagnosis of hepatocellular carcinoma(hepatoma) along with surgical resection is the most appropriate therapeutic modality. For this purpose there have been many reports con-cerning the diagnostic value of Lipiodol-CT scan. The authors selected 45 patients with hepatoma during the period of Feb. 1986 to Jan. 1988 who received a conventional CT scan hepatic angiography and a Lipiodol-CT scan. The results were as follows: 1. There was no statistical significance between serum AFP level and mass size morphology and amount of necrosis. 2. Tumor necrosis was observed in a single massive and multinodular type when the tumor size exceeded 5 cm 3. Pattern II on Lipiodol-CT homogenous accumulation of Lipiodol except for the area of inner necrosis was most frequently demonstrated which means that a tumor mass with hypervascularity and increased blood flow will attract Lipiodol better. 4. Lipiodol-CT was superior to conventional CT in detecting small daughter nodules. 5. When Lipiodol had accumulated well within the tumor non-change and decrease of the serum AFP level after Lipiodol injection occurred in 90% of cases which suggested clinical significance of therapeutic process.