Crude Aconiti Tubers were irradiated with microwave for 5 or 10 min with or without $NaHCO_3$. Ten min-irradiation reduced the contents of aconitine and mesaconitine to the level of those of commercially available processed Aconiti tuber power which is prepared with the high pressure-high temperature technique. The contents of benzoylaconine of the 10 min-irradiated Aconiti tubers were also comparable to those of commerciallized processed Aconiti tuber powder. However, irradiation with 1% $NaHCO_3$ soln. resulted in the drastic reduction of all the three above alkaloids.