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재래산양의 번식기에 있어서 혈중 Steroid Hormone 수준 변화에 관한 연구 III. 분만전후의 혈중 Progesterone 및 $20alpha$-Dihydroprogesterone
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  • 재래산양의 번식기에 있어서 혈중 Steroid Hormone 수준 변화에 관한 연구 III. 분만전후의 혈중 Progesterone 및 $20alpha$-Dihydroprogesterone
  • Studies on the Changes of Steroid Hormone Levels during the Reproductive Stage in Korean Native Goats III. Seroum Levels of Progesterone and $20alpha$-Dihydroprogesterone before and after Parturition
저자명
민관식,장규태,오석두,성환후,이병오,윤창현
간행물명
가축번식학회지
권/호정보
1992년|16권 2호|pp.149-155 (7 pages)
발행정보
한국동물번식학회
파일정보
정기간행물|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

The present study was conducted to find out the changes of progesterone and 20$alpha$-dihydroprogesterone(20$alpha$-OHP) levels before and after parturition, 4 pluriparous goats were offered for this experiment. Blood samples were taken from jugular vein on Days, 5, 3, 2 and 1 before parturition, the day of parturition, 1, 3, 5, 7 and 9 after parturition. The blood samples were centraifuged and stored at -2$0^{circ}C$ until hormone assay. The serum levels of progesterone and 20$alpha$-OHP were measrued by radioimmunoassay. The changes of serum progesterone level during peripartum period were characterized as a remarkable decrease. The progesterone level was 4.05$pm$0.52ng/ml on 56 days before parturition and decreased to 2.24$pm$0.38ng/ml on 1 day before parturition and 0.79$pm$0.09ng/ml on the day of parturition and the basal level was maintained through 9 days of postpartum period. The serum level of 20$alpha$-OHP during the peripartum period was 1.25$pm$0.21ng/ml on 5 days before paturition and increased to 1.32$pm$0.25 on 3 days and 1.59$pm$0.24ng/ml on 1 day before parturition, and reached a peak level of 1.78$pm$0.25ng/ml just prior to parturition and then decreased greatly to 0.31$pm$0.03ng/ml on 1 day postpartum and the basal level was remained until 9 days postpartum. The high serum level of 20$alpha$-OHP, which was peak just prior to parturition, was maintained for 2 days following the onset of remarkable decrease in the serum level of progesterone. From the above results, it was concluded that the enzyme 20$alpha$-hydroxysteroid dehydrogenase (20$alpha$-HSD) catalyzing the conversion of progesterone to a biologically inactive steroid, 20$alpha$-OHP was active properly in the luteal cells in Korean native goats.