This paper presents the results of fluidelastic instability analysis performed for the U-tube bundle of a Westinghouse model 51 steam generator, one of the recirculating types designed at an early stage, in which the principal region of external cross-flow is associated with the U-bend portion of tube. The prerequisites for this analysis are detailed informations of the secondary side flow conditions in the steam generator and the free vibration behaviours of the U-tubes. In this study, the three-dimensional two-phase flow field in the steam generator has been calculated employing the ATHOS3 steam generator two-phase flow code and the ANSYS engineering analysis code has been used to calculate the free vibration responses of specific U tubes under consideration. The assessment of the potential instability for the suspect U-tubes, which is the final analysis process of the present work, has been accomplished by combining the secondary side velocity and density distributions obtained from the ATHOS3 prediction with the relative modal displacement and natural frequency data calculated using the ANSYS code. The damping of tubes in two-phase flow has been deduced from the existing experimental data by taking into account the secondary side void fraction effect. In operation of the steam generator, the tube support conditions at the tube-to-tube support plate intersections due to either tube denting degradation or deposition of tube support plate corrosion products or ingression of dregs. Thus, various hypothetical cases regarding the tube support conditions at the tube-to-tube support plate intersections have been considered to investigate the clamped support effects on the forced vibration response of the tube. Also, the effect of anti-vibration bars support in the curved portion of tube has been examined.