The clinical study was done in 50 patients with acne who had been treated with acupuncture and herb-medicine. The results were as follows. There were 9 males and 41 females in sex. The peak age at onset was 21 - 30 years old(28 cases. 56%). The most commen chief complaint was itching(70%). As for digestion. 24 cases(48%) is poor and defecation disorder appeared 25cases 50%). difficult menstruation 20 cases (48.78%). Bohyulansintang(補血安神湯) was most use in treatments as 26.38%.As for treatment period. 25 cases(50%) were treated from 1 week to 3 weeks.