This study was performed to evaluate the effect of the Gamichunggantang on recovering from liver injury induced by d-galactosamine and ${alpha}$-naphthylisothiocyanate. and following results were obtained. 1. The increases of the serum GOT. GPT activities in mice induced by d-galactosamine and ${alpha}$-naphthylisothiocyanate were inhibited significantly by the administration of the Gamichunggantang. 2. The increases of the total cholesterol. triglyceride and blood urea nitrogen levels in mice induced by d-galactosamine and ${alpha}$-naphthylisothiocyanate were significantly inhibited by the administration of the Gamichunggantang. 3. The increase of the ALP activity in mice following liver injury induced by d-galactosamine and ${alpha}$-naphthylisothiocyanate were inhibited to an extend. but it was not significant. 4. It is considered that the efficacy of the Gamichunggantang on liver cell injury depends on its concentration rate.