This study presents an experimental investigation of the effect of the wake on mass transfer about a circular cylinder in crossflow. The flat-plate wake was generated by merging two mirror images of turbulent boundary layers that were well developed along the both sides of flat plate with a sharp trailing edge. The velocity field was measured by a hot-wire system and the mass transfer rate by a naphthalene sublimation method. The mixing and developing stages of the wake were addressed to identify flow conditions. The mass transfer effects of different developing stages of the wake was discussed in detail. It is noted that a local maximum appears not at the front stagnation point but at a point a little downstream when the cylinder is located in the nearwake region and much more elevated mass transfer rate is obtained compared to effect of free-stream turbulence.