A New environment SENSATION for circuit optimization and statistical analysis has been developed. It provides real time simulation and includes automatic algorithms to assist for reaching optimal solution. Furthermore, statistical analysis environment is presented which aids in Monte Carlo analysis. worst case corner analysis, and sensitivity analysis. These capabilities faciliate the characterization of the effects of several operating conditions and manufacture process paramenters on the design performances. We verify that the proposed methods can obtain the optimal solution of the objective function through several experimental results.