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모 공단지역 사무직 근로자들의 요중 N-acetyl-$eta$-D-glucosaminidase 역가에 관한 연구
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  • 모 공단지역 사무직 근로자들의 요중 N-acetyl-$eta$-D-glucosaminidase 역가에 관한 연구
저자명
김화성,리갑수,이성수,안규동,이병국,Kim. Hwa-Sung,Lee. Gap-Soo,Lee. Sung-Soo,Ahn. Kyu-Dong,Lee. Byung-Kook
간행물명
예방의학회지
권/호정보
1994년|27권 3호|pp.547-556 (10 pages)
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대한예방의학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

In order to identify the necessary information of biochemical Indices for renal effect of lead for the early detection in medical surveillance of lead worker, the reference values of urinary N-acetyl-$eta$-D-glucosaminidase (NAG) activities were studied with 205 office workers in one industrial complex area who were not exposed to lead occupationally. While study variables selected for lead exposure were blood lead (PbB), blood zinc protoporphyrin(ZPP) and $delta$-aminolevulinic acid (DALA) in urine, those for renal effect were urinary N-acetyl-$eta$-D-glucosaminidase (NAG), blood urea nitrogen (BUN), serum creatinine(Cr), serum uric acid (Ua), and urinary total protein(U-TP). The results obtained were as follows: 1. The mean values of blood lead, ZPP and DALA in all subjects were $14.39{pm}4.02{mu}g/dl,;21.61{pm}8.00{mu}g/dl,;and;2.73{pm}0.90mg/l$ respectively. 2. The mean value of urinary NAG activities in all subjects was $3.51{pm}2.01U/l$. The mean value of urinary NAG activities, which calculated from NAG activities divided by urinary creatinine concentration (CNAG), was $5.42{pm}5.53U/g$ creatinine and log-arithmic normal distributed. 3. The reference value of urinary NAG activity was 12.06 U/g creatinine(95% CU=10.57-14.76 U/g creatinine). 4. Logarithmic CNAG(r=0.781 p<0.0l), U-TP(r=0.670 p<0.01) and ZPP(r=0.172 p<0.05) showed statistically significant correlation with CNAG.