The meridians are energy pathways found in the interior organs of the body leading the bio-electrical energy the periphery of the body for its energetic supply and the meridians connect the individual acupuncture points. The acupucture points in turn serve for the interference with the bio-electric energy, thus made it measurable. It has been developed to a stage where one could stimulate the acupuncture-points in order to achieve organ effects in the body. To the contrast, Dr.Niboyet proved that the human skin contains points varing in their electrical roperties as to their surroundings. He also tried to send direct current through the skin taken from the body and derive it at other places of the skin characterized by the above mentioned meridians and acupuncture points. The body produces a potential in the organs to reach the acupuncture point via the meridians. The charge on the individual acupuncture point caused by the exactly difinable current of our mesurement device, creates a state of blance between the irritational potential, both of whcih are which are opposite to each other. The body processes the irritational current in the acupuncture point. Voll and Werner, as early as 1953, developed an instruments for applying electro-acupuncture on the skin without needle picks and the teaching from part of modern medicine after developing over recent years. Electro-acupucture is a comprechensive fterm for all procedures based on mesurements or thrapy derived from Oriental acupuncture, using modern electronics. As a result, I found the phenomena of the meridian during the disease. And It seems to be closely related between the meriduan and the disease. I think it must be researched profoundly and for the long time.