- 폐섬유화정에서 고해상 CT의 추적평가 및 폐기능 검사와 기관지 폐포 세척액과의 상관관계
- ㆍ 저자명
- 김민수,김양희,김세헌,박재성,김대호,최득림,김기정,이상무,어수택
- ㆍ 간행물명
- 대한방사선의학회지
- ㆍ 권/호정보
- 1995년|33권 2호|pp.215-220 (6 pages)
- ㆍ 발행정보
- 대한영상의학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
Purpose : To evaluate prospectively relationship between the extent of abnornelities of fibrosing alveolotroon high resolution CT and these of pulmonary function test, and bronchoalveolar lavage. Material and Methods : This study included 27 patients with pathologically proved UIP. We prospectively analyzed correlation of the extent of ground glass opacity, consolidation, irregular lines with honeycombing on initial CT scan and quantitative change of ground glass opacity on follow up CT scans with pulmonary function test(PFT) and bronchoalveolar lavage(BAL). Results : On initial CT scan, score of extent of disease significantly correlated with FEV1(r=-0.5148, p=0.0310) and DLco(r=-0.7102, p=0.0001). Proportion of indivisual cell in BAL was not correlated with ground glass opacity or extent of disease ; lymphocyte(p=-0.0165, r=0.9616), eosinophil(p=-0.0077), r=0.9832), neutrophil(p=-0.1732, r=0.5903). On follow up CT scan, quantitative change of ground glass opacity correlated with DLco/VA(r=-0.6825, p=0.0025) and TLC(r=0.5248, p=0.0429). Conclusion : The quantitative analysis of extent of disease on HRCT is useful for evaluation of clinical status. Also change of ground glass opacity on follow-up HRCT significantly correlated with improvement of diffusing capacity in fibrosing alveolitis.