The Plummer - Vinson syndrome Is characteristic difficulty In swallowing, iron defeciency anemia, and upper esophageal or hypopharyngeal web. It is rarely disease in Korea. We have experienced a case of the Plummer-Vinson syndrome, complaining of dysphagia with iron deficient anemia, hypopharyngeal web who was thirty - two years old woman has treated with bullous pemphigoid. The patient has treated sucessfully in the fasion with microsuspentional CO2 Laser for removal of hypopharyngeal web. We report one case with review of the literature.