We had undertaken a stellate ganglion block everyday for the treatment of a classic migraine patient who is a twenty seven a year old male. He had experienced a very severe and frequent attack two or three times a month for several years. after ten times of stellate ganglion block, a headache attack occurred mildly. Seventeen times of stellate ganglion block were undertaken totally. Now he feels better. The intensity and the frequency of headache attack are markedly decreased. The pathophysiology and theraphy of classic migraine are unclear. The mechanism of stellate ganglion block for classic migraine treatment is also unknown. However, we think the stellate ganglion block contributes the improvement of hypothalamic blood flow, the recovery of homeostasis, and the weakening of sympathetic overactivity.