- 뇌경색유발(腦梗塞誘發) 흰쥐의 국소뇌혈류량(局所腦血流量)과 뇌부종(腦浮腫)에 대한 이진탕(二陳湯)의 수(水) 및 메탄올추출엑스의 효과(效果)
- ㆍ 저자명
- 윤상협,민병일,류재환,Yun. Sang-Hyeop,Min. Byeong-Il,Ryu. Jae-Hwan
- ㆍ 간행물명
- 大韓韓醫學會誌
- ㆍ 권/호정보
- 1996년|17권 2호|pp.161-167 (7 pages)
- ㆍ 발행정보
- 대한한의학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
For the purpose of developing a new drug against cerebral infarction, we chose Ijintang which is frequently applied in the field of Jung Pung of traditional medicine. From this formula, water extract and methanol extract were prepared respectively. Animals were divided into three groups; control group, water extract medicated group, methanol extract treated group. water extract was given 195mg/kg orally and methanol extract, 165mg/kg for 2 weeks in case of cerebral edema and 1 month in regional cerebral blood flow. On the regional cerebral blood flow, the drug medicated groups showed no significant changes as compared gith control group. There was no significant difference on the cerebral edema among the groups. According to the results above, it is suggested that oral medication of water extract and methanol extract from Ijintang have no effect on the change of rCBF and edema after acutely induced cerebral infarction. However, it is thought that modification of administration method and development of new animal model for traditional medicine are needed.