Oil-film flow visualizations and three-dimensional flow measurements using a five-hole probe have been conducted to investigate three-dimensional flow characteristics and total pressure losses of a row of film-cooling jets injected in spanwise direction. For several span-to-diameter ratios, experiments are performed in the case of three velocity ratios of 0.5, 1.0 and 1.5. The flow measurements show that downstream flow due to the injection is characterized by a single streamwise vortex instead of a pair of counter-rotating vortices, which appear in the case of streamwise injection, and the vortex strength strongly depends on the velocity ratio. Regardless of the velocity*y ratio, presence of the spanwise film-cooling jets always produces total pressure loss, which is pronounced when the velocity ratio is large. It has also been found that the production of the total pressure loss is closely related to the secondary vortical flow. In addition, effects of the span-to-diameter ratio on the flow and total pressure loss are discussed in detail.