Sr, Nd and Pb isotopic characteristics of alkaline lavas and tholeiites in Cheju Island show that the isotopic compositions of the former slightly overlap, but have relatively more depleted than the latter. However, in viewpoint of the two eruptional stratigraphies of tholeiites, the isotopic compositon of the older one is similar to those of alkaline rocks in Lava Plateau Stage after Lee (1982). These suggest that the parental magmas of alkaline lavas and tholeiites might have originated from the homogenous mantle sourve and that the characteristics of the mantle source to be partially melted might be different between the eruption stages. The isotopic signatures of the bolcanic rocks in Cheju Island overlap with those in Samoa Islands and South China Basin, indicating the DMM-EM IImixing trend. This is distingushed from the DMM-EM I trend of the Cenozoic volcanic rocks in Korea except for cheju Island and Northeastern China. The modelled binary mixing calculation between MM and EM IImaterials indicates that the mantle source of the volcanic rocks in Cheju Island has been mixed about less than 10% of enriched mantle material (EM II) with depleted mantle material (DMM). Concerned with the indentation model between North China Block (NCB) and South China Block (SCB) after Yin an Nie (1993), we suggest that the distinct isotopic features of DMM-EM I and DMM-EM IIof the Cenozoic volcanic rock in Korea as well as China can be explained by the difference of the nature of subcontinental lithospheric mantle as enriched mantle materials, i.e. EM I of NCB, while EM II of SCB.