This paper deals with a numerical study of the dynamic response of rubber oil seals for rotating shaft when interference as well as static and dynamic eccentricities are present. In loss of contact conditions the dynamic curve of oil seals is numerically simulated using the FEM package MSC/NASTRAN. The direct integration method is selected to analyze the time domain response of the seal lip-shaft contact. The computed results based on the experimental data indicate that the increased rotating speed may produce the gap separation between lip edge of rubber seals and shaft. These results will be very useful in predicting the dynamic leakage due to contact behaviors of rubber oil seals under dynamic conditions.