There are many different views of the opinion that smoking decreased the HDL cholesterol. So this cross-sectional study was attempted to find the influence which smoking, alcohol and weight affect HDL cholesterol. They were two groups;smoking group(409 males) and nonsmoking group(213 males). And HDL cholesterol, triglyceride, and total cholesterol of smoking group were compaired to them of nonsmoking group. Also the variables of age, relative weight, and alcohol were compaired. The HDL cholesterol of nonsmoking group was 47.2$pm$10.1 mg/dl and the HDL cholesterol of smoking group was 45.5$pm$10.7mg/dl. So there were no statistical difference. As smoking was increased in amount, HDL cholesterol was decreased slightly. According as the alcohol intake increases, especially only the HDL cholesterol of the moderate alcohol intake(101-200gm/week) group was significantly increased(P<0.05). As relative weight increases, HDL cholesterol were significantly decreased(P=0.007). Smoking was not statistical difference of HDL cholesterol. Moderately alcohol intake group(101-200gm/week) were increased the HDL cholesterol(P<0.05). Only relative weight was statistically decreased the HDL cholesterol(P<0.01). Multiple regression results that relative weight and alcohol were significant variable of the level of HDL cholesterol.