This study is to develop a practical calculation method of hydrodynamic force and motion response on very large floating structures of multiple legs. To investigate the effecr of hydrodynamic interfaction and of free surface on the reaponses of very large floating structures in regular waves, four kind of models are considered, ie. 1, 4, 64, 21248 column with footing. Based upon the results of this study, it is found that the middle parts of very large floating structures have small diffration effects. Therefore only out side parts are used to determine the hydrodynamic forcea for taking into account the effects of interaction.