In this paper, we analyze the multipath fading and the inter-satellite interference considering the satellite mobility in the LEO mobile satellite communication networks and evaluate the link perfodrmance for various wave propagation environments and reliabilities of communiation system. Multipath fading is estimated by analyzing the variation of fading margin for the satellite motion in rural, urban and suburban environments. The inter-satellite interferences are classified into 8 bypes with respect to interference path. The interferences evaluated in the paper are as follows:intra-LEO satellite interference, inter-LEO satellite interference, and GEO satellite to LEO satellite interference. As a conclusion, this apaper analyzes the change of elevation anagle and propagation distance with respect to time in the LEO satellite netwoek and prosents the variation of link margin continuously.