At the result of data analysis with sample survey, oriental medicine clinics which treat particular kinds of illness with specialization make the profit of 1.6 times and the expense of 0.74 times more than those which treat general diseases, namely, the former gain the profit of about 2.9 times more than the latter. After excluding other variables which affect in the profit of oriental medicine clinics with multiple regression model, when considering only advantage of treatment for particular kinds of illness, specialized oriental medicine clinics win the more profit of 18.3 percent than general oriental medicine clinics. The specialization of oriental medicine clinics can become one of the positive measures in the situation of enlargement of medical of oriental medicine, falling of oriental medicine price and conflict of western and oriental medicine, etc. The specialization can help western medicine replace with oriental medicine, and level and scientific system of oriental medicine improve. Medical service for particular diseases, one of the better devices for improving profit of oriental medicine clinics, can theoretically make more advantage of oriental medicine clinics through measure of price discrimination than general medicine clinics.