The objective of this study is to investigate the role of large-scale coherent structures in a spatially developing plane mixing layers. To achieve this, we have to look into the mutual interactions between three-dimensional large-scale coherent structures and the mean flow. Our attention will be focused on the energy exchange mechanism between the various modes, and the effects of the nonlinear evolution of the phases of the interacting modes. Linear stability of the three-dimensional viscous shear layer is formulated and solved as the basis for the solution of the nonlinear formulation based on the energy method. The importance of the initial conditions that may affect the evolution of the flow has been examined. It has been numerically calculated the nonlinear effects arising from the interactions among the three-dimensional large-scale coherent structures in a spatially developing plane mixing layers. The results of this study provide useful parametric information for the control of shear layer in practical applications in the mixing and transport augmentation.