Vibration test fixture is used in random vibration control testing. The specified reference spectrum should be transmitted equally to the specimen attachment points on the fixture. In most practical cases, however, spectrum at each of specimen attachment points may be quite different from the specified reference spectrum because of the dynamic characteristics of vibration test fixture. This paper proposes the method of experimental dynamic modification of fixture system for vibration test so that the reference spectrum can be transmitted to the specimen attachment points without distortion. The stiffness of mounts of specimen and the thickness of fixture are considered as design variables. The frequency response functions of specimen used for input data are obtained from vibration testing, and the frequency response functions of fixture are obtained from finite element modeling. The sensitivities of frequency response functions at specimen attachment points to the mount stiffness are derived from synthesis method of transfer function. And the sensitivities to the thickness of fixture are also derived from finite element modeling. The presented method is verified by computer simulation and vibration testing.