An analytical procedure on the base of the substructure synthesis and assumed modes method is developed to investigate the flexibility effect of bladed disk assembly on vibrational modes of flexible rotor system. In modeling the system, Coriolis forces, gyroscopic moments, and centrifugal stiffening effects are taken into account. The coupled vibrations between the shaft and bladed disk are then extensively investigated through the numerical simulation of simplified models, with varying the shaft rotational speed and the prewist and stagger angles of the blade. It is found that the Coriolis and inertia forces and the inertia torque, which are induced by the one nodal diameter modes of the bladed disk and vary depending upon the stagger and prewist angles, lead to the coupled motions of the shaft and the bladed disk.