The relationships of El Nino and La Nina with both temperature and precipitation in South Korea is studied. Monthly temperature and precipitation are analyzed using harmonic analysis to identify region, magnitude and season that have responses associated with El Nino and La Nina. The first harmonic is extracted from a 24 month El Nino and La Nina composite at each station. The regions are identified by the similarity in the phase of the harmonic vectors. The responses of precipitation to El Nino and La Nina are found in the all regions. However, the response of precipitation to El Nino and La Nina is identified only in the southern region. In addition, statistical significance for response periods is investigated through cross correlation analysis. Once an El Nino and a La Nina event set in, the results of this analysis can provide an efficient information for the management of water resources, agriculture and environment.