An analysis of dynamic responses is carried out on monoclinic anisotropic system due to a buried harmonic line source. The load is in the form of a normal stress acting along an arbitrary axis on the plane of symmetry within the orthotropic materials: In case that the line load is acting along the symmetry axis normal to the plane of symmetry, plane wave equation is coupled with verital shear wave and longitudinal wave. However, if the line load is acting along an arbitrary axis normal to the plane of symmetry, plane wave equation is coupled with vertical shear wave, longitudinal wave and horizontal shear wave. We first considered the equation of motion in a reference coordinate system, where the line load is coincident with a symmetry axis of the orthotropic material. Then the equation of motion is transformed into one with respect to general coordinate system with azimuthal angle by using transformation tensor. Plane wave solutions of monoclinic systems are derived for infinite media. Finally complete solutions for the plane harmonic wave are obtained by calculating the inverse of the integral transforms, in which bulk wave poles are avoided by deforming the contour of the integration to the complex plane. Numerical results for examples of orthotropic material belonging to monoclinic symmetry are demonstrated.