A numerical method is proposed to optimize automotive cam profiles. An acceleration curve of a cam follower motion is described by Hermite spline curves. Because of the intrinsic characteristics of the Hermite curve, it is possible to design an acceleration curve with arbitrary shape. Design variables in the optimization problem are location of control points which define the acceleration curve. Objective function includes dynamic performances as well as kinematic properties of a valve train. Similar optimization procedure was also performed using Polydyne cam profile synthesis method. Optimized profiles using the Hermite curve are proved to be superior to those using the Polydyne method.